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Treatment of Vasogenic Edema by Cdp-Choline, a Metabolic Precursor of Phospholipids (Experimental and Clinical Data)

  • F. Cohadon
  • M. Rigoulet
  • N. Averet
  • E. Richer

Abstract

The available biochemical data about CDP Choline as an intermediate in lipid metabolism, as well as its use as a drug in a number of pathological conditions of the brain, have been extensively reviewed5. CDP Choline may be considered to enhance the repair of phospholipid structures, initiating the present experimental study on an animal model of vasogenic brain edema. The results obtained on the model led to its clinical application in a series of severe head injuries, a condition in which brain edema is supposed to play an important role.

Keywords

Brain Edema VASOGENIC Edema Severe Head Injury Brain Water Content Cold Injury 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • F. Cohadon
    • 1
    • 2
  • M. Rigoulet
    • 1
    • 2
  • N. Averet
    • 1
    • 2
  • E. Richer
    • 1
    • 2
  1. 1.Laboratoire de Neurochirurgie Expérimentale — E.R.A. C.N.R.S. 843Université de Bordeaux IIBordeauxFrance
  2. 2.Service de Neurochirurgie A — Hôpital Pellegrin/tripodeBordeauxFrance

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