Advertisement

Shift of Water in the Brain by Intravenously Administered Hypertonic Solutions

  • Akira Gega
  • Shozaburo Utsumi
  • Yoshiki Iida
  • Noriuki Iida

Abstract

Control of intracranial pressure by hypertonic solutions remains an important form of treatment, although a rebound phenomenon may result. The authors studied concentrations of hypertonic solutions in blood and CSF, as well as CSF outflow volume in patients subjected to monitoring of intracranial pressure. This was to analyze changes of intracranial water content during treatment.

Keywords

Intracranial Pressure Glycerol Concentration Glycerol Solution Hypertonic Solution Rebound Phenomenon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Gega A, Utsumi S, Iida Y, Iida N, Tsunoda S: Analysis of the wave pattern of CSF pulse wave. Intracranial pressure IV. Springer-Verlag. Berlin Heidelberg New York, 188–190 (1980).CrossRefGoogle Scholar
  2. 2.
    Guisado R, Arieff AI, Masry SG: Effects of glycerol infusion on brain water and electrolytes. Am J Physiol, 277, 865–872 (1974).Google Scholar
  3. 3.
    Lundberg N: Continuous recording and control of ventricular fluid pressure in neurosurgical practice. Ejnar Munksgaard, Copenhagen, 158 (1960).Google Scholar
  4. 4.
    Meyer JS, Fukuchi Y, Shimazu K, Okuchi T, Ericsson AD: Effect of intravenous infusion of glycerol on hemispheric blood flow and metabolism in patients with acute cerebral infarction. Stroke 3: 168–180 (1972).CrossRefGoogle Scholar
  5. 5.
    Sears SS: Nonketonic hyperosmolar hyperglycemia during glycerol therapy for cerebral edema. Neurology, 26, 89–94 (1976).CrossRefGoogle Scholar
  6. 6.
    Sloviter HA, Shimkin P, Suhara K: Glycerol as a substrate for brain metabolism. Nature, 210, 1334–1336 (1966).CrossRefGoogle Scholar
  7. 7.
    Waterhous JM, Coxon RV: The entry of glycerol into brain tissue. J Neurol Sci 10, 305–311 (1970).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Akira Gega
    • 1
  • Shozaburo Utsumi
    • 1
  • Yoshiki Iida
    • 1
  • Noriuki Iida
    • 1
  1. 1.Department of NeurosurgeryNara Medical UniversityNaraJapan

Personalised recommendations