Advertisement

An Attempt to Automate Control of Cerebral Edema

  • David J. Price
  • John Mason

Abstract

The preservation of an adequate cerebral perfusion pressure is an essential component of the management of patients in coma following severe head injury or a spontaneous intracranial hemorrhage. After evacuation of any hematoma,adherence to such a principle demands both careful control of cerebral edema and maintenance of arterial normotension.

Keywords

Cerebral Edema Intracranial Hypertension Severe Head Injury Head Injured Patient Mannitol Administration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Adams JH, Graham DI: The relationship between ventricular fluid pressure and the neuropathology of raised intracranial pressure. Neuropathol Appl Neurobiol 2: 323–332 (1976).CrossRefGoogle Scholar
  2. 2.
    Becker DP, Vries JK: The alleviation of increased intracranial pressure by the chronic administration of osmotic agents. In Brock M, Dietz H (Eds.): “Intracranial Pressure”. New York, Springer-Verlag 309–315 (1972).CrossRefGoogle Scholar
  3. 3.
    Bowers SA, Marshall LF: Outcome in 200 consecutive cases of severe head injury treated in San Diego County: a prospective analysis, Neurosurgery 6: 237–242 (1980).CrossRefGoogle Scholar
  4. 4.
    Bruce DA, Schut L, Bruno LA, Woods JH, Sutton LN: Outcome following severe head injuries in children. J Neurosurg 48: 679–688 (1978).CrossRefGoogle Scholar
  5. 5.
    Burke AM, Quest DO, Chien S, Cerri C: the effects of mannitol on blood viscosity. J Neurosurg 55: 550–553 (1981).CrossRefGoogle Scholar
  6. 6.
    Graham DI, Adams JH, Doyle D: Ischaemic brain damage in fatal nonmissile head injuries. J Neurol Sci 39: 213–234 (1978).CrossRefGoogle Scholar
  7. 7.
    Jennett B, Teasdale G, Fry J, Braakman R, Minderhoud J, Kurze T: Treatment for severe head injury. J Neurol Neurosurg Psychiatry 43: 289–295 (1980).CrossRefGoogle Scholar
  8. 8.
    Johnston IH, Harper AM: The effect of mannitol on cerebral blood flow. An experimental study. J Neurosurg 38: 461–471 (1973).CrossRefGoogle Scholar
  9. 9.
    Marshall LF, Smith RW, Rauscher LA, Shapiro HM. Mannitol dose requirements in brain-injured patients. J Neurosurg 48: 169–172 (1978).CrossRefGoogle Scholar
  10. 10.
    McGraw CP, Alexander E Jr, Howard G: Effect of dose and dose schedule on the response of intracranial pressure to mannitol. Surgical Neurology 10: 127–130 (1978).Google Scholar
  11. 11.
    Miller JD, Becker DP, Ward JD, Sullican HG, Adams WE, Rosner MJ: Significance of intracranial hypertension in severe head injury. J Neurosurg 47: 503–516 (1977).CrossRefGoogle Scholar
  12. 12.
    Miller JD, Butterworth JF, Gudeman SK, Faulkner JE, Choi SC, Selhorst JB, Harbison JW, Lutz HA, Young HF, Becker DP: Further experience in the management of severe head injury. J Neurosurg 54: 289–299 (1981).CrossRefGoogle Scholar
  13. 13.
    Price DJ, Dugdale RE, Mason J: The control of ICP using three asynchronous closed loops. In: Shulman K, Marmarou A, Miller JD, Becker DP, Hockwald GM, Brock M (Eds.). Intracranial pressure, vol. IV. Springer, Berlin Heidelberg New York, 395–399 (1980).Google Scholar
  14. 14.
    Price DJ: Head injuries. In: Tinker J, Rapin M (Eds.) Care of the critically ill patient. Springer, Berlin Heidelberg New York (in press) (1982).Google Scholar
  15. 15.
    Saul TG, Ducker TB: Effect of intracranial pressure monitoring and agressive treatment on mortality in severe head injury. J Neurosurgery 56: 498–503 (1982).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • David J. Price
    • 1
  • John Mason
    • 1
  1. 1.WakefieldEngland

Personalised recommendations