The Effect of Corticosteroids at the Level of the Arachnoid Ville
Corticosteroids, particularly dexamethasone, have been used extensively in neurosurgical practice in an attempt to reduce the brain edema which frequently accompanies intracranial pathology7,8. Where it has been possible, the pretreatment of patients before neurosurgical operations has reduced the morbidity frequently associated with some procedures13, in spite of many studies there is still little agreement on the mode of action of steroids in the prevention or resolution of brain edema6, in the present study the effect of dexamethasone on the conduction of cerebrospinal fluid (CSF) across the isolated sagittal sinus has been examined.
KeywordsBrain Edema Lower Chamber Drainage Pathway Conduction Rate Arachnoid Villus
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