Effect of Glucocorticosteroids in a Human Model of Cerebral Edema Studied by Computer Tomography
Radio frequency coagulation lesions in the thalamus, as performed in the stereotactic treatment of tremors, can be demonstrated by computer tomography (CT)1,2,3,4,6. We have previously reported on the appearance of thalamic lesions in sequential postoperative CT scans3. The fresh lesion was seen as a rounded area of decreased attenuation with a central core of usually increased attenuation. During the first few days up to a week after the operation the area of decreased attenuation grew in size and then slowly diminished. This change in size was interpreted as reflecting development and resolution of edema around the area of tissue destruction. As stereotactic thalamotomy is performed with little variation in the procedure causing brain injury it was thought that it might serve as a model for studies on cerebral edema in man, using CT for assessment of the edema.
KeywordsComputer Tomography Cerebral Edema Steroid Group Thalamic Lesion Consecutive Time Period
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