Comparison of the Potential of Nitroprusside and Nitroglycerin to Produce Swollen Brain

  • Harold D. Portnoy
  • Michael Chopp
  • Craig Branch
  • Michael Shannon


Controlled arterial hypotension is frequently used during intracranial surgery of vascular tumors, arteriovenous malformations and aneurysms to reduce hemorrhage and prevent rupture of the aneurysm1,2,3,13. In addition, intravenous vasodilators have been used for the control of acute hypertensive crisis associated with malignant hypertension associated with rupture of an intracranial aneurysnr9.


Cerebral Blood Flow Sodium Nitroprusside Systemic Arterial Pressure Vasomotor Tone Impaired Autoregulation 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Harold D. Portnoy
    • 1
  • Michael Chopp
    • 1
  • Craig Branch
    • 1
  • Michael Shannon
    • 1
  1. 1.Oakland Neurological ClinicBloomfield HillsUSA

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