The Time Course and Distribution of Water in the Resolution Phase of Infusion Edema
Relatively little is known of the clearance mechanisms in the vasogenic form of brain edema. According to Klatzo7 the ingestion of the exudate by astrocytes and its digestion are the primary mechanisms involved in clearing the issue of edema fluid. Reulen et al14 postulated that the edema fluid follows a downhill pressure gradient by bulk flow and enters the ventricle where it is cleared by the CSF. The effectiveness of the clearance mechanism in acute and chronic stages of brain edema has not been resolved. Moreover, it has been suggested by Cserr5 and Bradbury2, that edema fluid that flows into the CSF from the brain interstitium may be cleared by a lympathic pathway. The importance of this route in clearance of edema is unclear.
KeywordsBrain Edema Bulk Flow Albert Einstein College Cold Injury Edema Fluid
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