Modifying Cerebrovascular Responses in Focal Brain Edema

  • P. L. Reilly


The response of the cerebrovascular system to injury is complex. Autoregulation is easily impaired by minor injury7, yet in severe injuries with edema, cerebral blood flow (CBF) may remain constant during arterial hypertension. That this is not true autoregulation has been shown in several previous studies5,7,8. Indeed, such a response indicates a degree of derangement of vascular control beyond simple pressure-passive loss of autoregulation. During recovery from severe injuries, a pressure-passive relationship between CBF and perfusion pressure may be restored before recovery of normal autoregulation.


Cerebral Blood Flow Arterial Hypertension Evans Blue Systemic Arterial Pressure Tissue Pressure 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • P. L. Reilly
    • 1
  1. 1.Department of NeurosurgeryRoyal Adelaide HospitalSouth Australia

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