Effect of Drugs on Local Cerebral Glucose Utilization in Traumatized Brain: Mechanisms of Action of Steroids Revisited

  • Hanna M. Pappius
  • Leonhard S. Wolfe


It may seem inappropriate to include in this volume work which does not deal directly with cerebral edema. However, we make no apologies for this fact since our present studies on the mechanisms by which injury to the brain causes functional neurological disturbances have evolved from a longstanding interest of one of us in processes underlying the development of brain edema and its consequences. We believe that the implications of our findings are pertinent to consideration of any condition associated with functional disturbances which are generally, rightly or wrongly, ascribed to cerebral edema.


Arachidonic Acid Brain Edema Cerebral Edema Injured Brain Functional Disturbance 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Hanna M. Pappius
    • 1
  • Leonhard S. Wolfe
    • 1
  1. 1.The Donner Laboratory of Experimental Neurochemistry Montreal Neurological Institute and HospitalMcGill UniversityMontrealCanada

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