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Brain Edema in Cerebral Malaria: A Comparative Clinical and Experimental, Ultrastructural and Histochemical Study

  • C. Jerusalem
  • T. Polder
  • K. Kubat
  • M. Wijers-Rouw
  • Phan Trinh

Abstract

In several countries of the Western-Pacific region, for instance Vietnam and Cambodia, malaria tropica (P. falciparum) had become a serious problem because of the resistance of plasmodia to chloroquine (100%) quinine and Fansidar(R) (about 20%). Mortality among children hospitalized because of acute P. falciparum infection is about 48% while about 22% of adults die of this disease. The main cause of death is a cerebral syndrome with clinical manifestations of deep coma, convulsions and terminal cardiac and/or respiratory arrest.

Keywords

Brain Edema Cerebral Malaria Perivascular Space Plasmodium Berghei Petechial Hemorrhage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • C. Jerusalem
    • 1
  • T. Polder
    • 1
  • K. Kubat
    • 2
  • M. Wijers-Rouw
    • 1
  • Phan Trinh
    • 3
  1. 1.Dept. of Cytology and HistologyUniversity of NijmegenThe Netherlands
  2. 2.Dept. of Cytology and PathologyUniversity of NijmegenThe Netherlands
  3. 3.Choray HospitalHoChiMinh CityVietnam

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