Ultrastructure of Cerebral Vessels in Hypoosmolar Edema

  • J. Cervos-Navarro
  • J. Artigas


Conventional light microscopy of osmotic brain edema yielded only unspecific findings, e.g. prominent diffuse glial swelling at high doses but did not lend itself to accurate quantitation. This explains the discrepancy between physiological, or biochemical findings on osmotic edema and its anatomical aspects9,7,11,6. The aim of our experiments was to obtain quantitative data on the topography of brain volume changes during water intoxication in relation to structural findings. Some of the particularly interesting ultra-structural findings are discussed in this presentation.


Tight Junction Horse Radish Peroxidase Water Intoxication Conventional Light Microscopy Central Nervous Tissue 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • J. Cervos-Navarro
    • 1
  • J. Artigas
    • 1
  1. 1.Department of NeuropathologyKlinikum Steglitz, Freie Universität BerlinBerlinGermany

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