Morphological Changes in the Aging Mammalian Pancreas

  • Bernard G. Slavin
  • Wendelin J. Paule
  • Sol Bernick


A comprehensive description of morphological and cytological changes in the aging mammalian pancreas has not been reported. What works have been published consist of light microscopic descriptions of a variety of histopathologic lesions in both the aging exocrine and endocrine pancreas. While this chapter deals specifically with the area of age-related cytomorphologic changes in the mammalian pancreas, emphasis will be placed on a description of the endocrine pancreas. This is not difficult to understand in light of the relationship of the endocrine pancreas to diabetes mellitus, a disease mainly of the aged population.


Islet Cell Pancreatic Islet Acinar Cell Ductal Cell Exocrine Pancreas 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Bernard G. Slavin
    • 1
  • Wendelin J. Paule
    • 1
  • Sol Bernick
    • 1
  1. 1.Department of Anatomy and Cell BiologyUniversity of Southern California School of MedicineLos AngelesUSA

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