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Aging at the Neuromuscular Junction

  • Dean O. Smith
  • Julie L. Rosenheimer

Abstract

Aging is manifest in many ways. Some are subtle while others are quite pronounced. In the nervous system, aging is particularly evident, for there are distinct behavior changes. Impaired motor coordination and reduced physical strength are among the most apparent and widespread attributes of senescence. For example, the rates and the magnitudes of various reflex responses, including simple movements of a finger or a foot, generally decrease. This is associated with a progressive decline in muscle strength after about 25 years of age (Åstrand and Rodahl, 1977). Furthermore, the rate of decrease in strength is greater for the leg and trunk muscles than for the arm muscles.

Keywords

Synaptic Vesicle Nerve Terminal Neuromuscular Junction Phrenic Nerve Extensor Digitorum Longus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Dean O. Smith
    • 1
  • Julie L. Rosenheimer
    • 1
  1. 1.Department of PhysiologyUniversity of WisconsinMadisonUSA

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