N-Nitrosamine Mutagenicity Using the Salmonella/Mammalian-Microsome Mutagenicity Assay
The Salmonella / mammalian-microsome mutagenicity assay has been used extensively to test a variety of chemicals.(1) The results of many of the assays employed soon after the Ames test began to gain worldwide acceptance showed that nitrosamines, as a chemical class, did not demonstrate a consistent correlation between mutagenicity and carcinogenicity.(2) However, the more this testing was used, the more information was uncovered that showed the flexibility and adaptability of the assay.
KeywordsMutagenic Activity Liver Homogenate Potent Mutagen Mutagenic Response Of300 Chemical
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