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Biophysics and Microphysiology of Synaptic Transmission in Hippocampus

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Brain Slices

Abstract

Most of what is known about the microphysiology and biophysics of synaptic transmission has derived from the study of just three preparations: the vertebrate and arthropod neuromuscular junctions and the squid giant synapse (Katz, 1969; Martin, 1977; Takeuchi, 1977). Although the general facts and laws gleaned from these three classical preparations probably apply also to cortical synapses, this inference remains an article of faith. Furthermore, there are structural and functional specializations in the cortex that cannot readily be addressed in the three classical preparations.

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Authors and Affiliations

  1. Program in Neuroscience, Section of Neurophysiology, Department of Neurology, Baylor College of Medicine, Houston, Texas, 77030, USA

    Daniel Johnston

  2. Department of Cellular Neurophysiology, Division of Neurosciences, City of Hope Research Institute, Duarte, California, 91010, USA

    Thomas H. Brown

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  1. Daniel Johnston
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  1. University of North Carolina, Chapel Hill, North Carolina, USA

    Raymond Dingledine

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Johnston, D., Brown, T.H. (1984). Biophysics and Microphysiology of Synaptic Transmission in Hippocampus. In: Dingledine, R. (eds) Brain Slices. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4583-1_4

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  • DOI: https://doi.org/10.1007/978-1-4684-4583-1_4

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