Brain Slices pp 297-311 | Cite as

Locus Coeruleus Neurons

  • John Williams
  • Graeme Henderson
  • Alan North


The nucleus locus coeruleus (LC) is a group of neurons situated close to the floor of the fourth ventricle at the upper border of the pons. The cells of the rat LC are homogeneous by certain criteria. Virtually all the cells contain noradrenaline and its synthesizing enzymes (Dahlström and Fuxe, 1964; Pickel et al., 1979), and, in the anesthetized animal, they all discharge action potentials at a rather regular and slow rate (0.5 to 2 Hz) (Korf et al., 1974).


Reversal Potential Noradrenergic Neuron Synaptic Potential Locus Coeruleus Neuron Calcium Spike 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • John Williams
    • 1
  • Graeme Henderson
    • 2
  • Alan North
    • 1
  1. 1.Neuropharmacology Laboratory, Department of Nutrition and Food ScienceMassachusetts Institute of TechnologyCambridgeUSA
  2. 2.Department of PharmacologyUniversity of CambridgeCambridgeEngland

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