Immunopathology of Parasitic Diseases: A Conceptual Approach

  • S. Michael Phillips
  • Edward G. Fox
Part of the Contemporary Topics in Immunobiology book series (CTI, volume 12)


The pathology caused by parasites, the most prevalant infectious diseases of humankind, can be divided into two major aspects: the first relates to the effects of the parasite per se, e.g., iron deficiency anemia, secondary to blood loss caused by intestinal nematodes; hemolytic anemia, secondary to intracellular protozoans; or hepatobiliary fibrosis, secondary to toxic products produced by intraductal trematodes. However, in many parasitic conditions there is limited pathology directly attributable to the parasite. Most host morbidity is related to the immunoinflammatory response of the host to the parasite. This reaction is the principal subject of this chapter.


Parasitic Disease Granuloma Formation Schistosoma Mansoni Schistosoma Japonicum Filarial Infection 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • S. Michael Phillips
    • 1
  • Edward G. Fox
    • 1
  1. 1.Allergy and Immunology SectionUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

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