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Central Serotonin Receptors

  • M. Hamon
  • S. Bourgoin
  • S. El Mestikawy
  • C. Goetz

Abstract

With the catecholamines (dopamine, norepinephrine, and epinephrine), serotonin (5-HT, 5-hydroxytryptamine) is one of the best known biogenic amine neurotransmitters in the CNS. During the past 20 years, an abundant literature has been devoted to this molecule, exploring its distribution, metabolism, and functions. However, investigations on the specific receptors involved in serotoninergic neurotransmission really began only in 1974 with the introduction of binding assays using tritium-labeled ligands with high specific radioactivities. The present review is an attempt to summarize the most important findings reported on central 5-HT receptors, mainly during the last 7 years.

Keywords

Adenylate Cyclase Adenylate Cyclase Activity Tryptophan Hydroxylase Brain Membrane Apparent Affinity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • M. Hamon
    • 1
  • S. Bourgoin
    • 1
  • S. El Mestikawy
    • 1
  • C. Goetz
    • 1
  1. 1.114, Collège de FranceGroupe NB, INSERM UParis, Cedex 05France

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