Circulating Immune Complexes

  • Dinesh Kumar


Antigens, self or foreign, induce an immune response leading to production of specific antibodies that interact with the inciting antigens and may form antigen—antibody (immune) complexes. An immune response is normally developed as a defense mechanism which eliminates and neutralizes the undesirable antigens. In addition, immune complexes have a regulatory role in both the cellular and humoral immune responses by virtue of their capacity to interreact with Fc and complement receptor-bearing lymphocytes and macrophages. The formation of the immune complexes under certain circumstances could be pathogenic, resulting in disease states.


Immune Complex Raji Cell Islet Cell Antibody Insulin Antibody Immune Complex Disease 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Dinesh Kumar
    • 1
  1. 1.Division of Diabetes and Clinical NutritionUniversity of Southern California School of MedicineLos AngelesUSA

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