Effects of Glycerol on Purine Metabolism in Rat Liver Cells

  • Christine Des Rosiers
  • Marcel Lalanne
  • Joan Willemot
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 165)


Glycerol phosphorylation in liver cells produces a rapid depletion of inorganic phosphate (Pi) and adenine nucleotides (1–3). These effects are similar to those produced by fructose (3,4). In addition, fructose administration to mice or humans also causes an increase in purine synthesis de novo (5–7).


Adenine Nucleotide Purine Nucleoside Purine Metabolism Purine Nucleotide Purine Synthesis 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Christine Des Rosiers
    • 1
  • Marcel Lalanne
    • 1
  • Joan Willemot
    • 1
  1. 1.Département de Biochimie, Faculté de MédecineUniversité LavalCanada

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