The Effect of Beer Ingestion on Plasma and Urine Uric Acid in Gout and Normouricaemic Subjects
A relationship between hyperuricaemia, gout and excessive alcohol consumption is well established. The increase of serum lactate which follows alcohol ingestion may impair renal urate excretion and is claimed to be the principal mechanism.1 Such an effect has been shown in studies using alcohol in amounts which have exceeded those commonly consumed by gout patients in our experience.2 Furthermore, previous experiments have usually involved fasting subjects so that the role of lactate on urate clearance has not been clearly distinguishable from that of fasting alone.3
KeywordsArthritis Lactate Purine Colchicine Gout
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