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The Effect of Beer Ingestion on Plasma and Urine Uric Acid in Gout and Normouricaemic Subjects

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Purine Metabolism in Man-IV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 165))

Abstract

A relationship between hyperuricaemia, gout and excessive alcohol consumption is well established. The increase of serum lactate which follows alcohol ingestion may impair renal urate excretion and is claimed to be the principal mechanism.1 Such an effect has been shown in studies using alcohol in amounts which have exceeded those commonly consumed by gout patients in our experience.2 Furthermore, previous experiments have usually involved fasting subjects so that the role of lactate on urate clearance has not been clearly distinguishable from that of fasting alone.3

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References

  1. D.S. Newcombe, Ethanol metabolism and uric acid. Metabolism 21: 1193 (1972)

    Article  PubMed  CAS  Google Scholar 

  2. C.S. Lieber, D.P. Jones, M.S. Losowsky, C.S. Davidson, Interrelation of uric acid and ethanol methabolism in man. J. Clin. Invest. 41: 1863 (1962)

    Article  PubMed  CAS  Google Scholar 

  3. M.J. Maclachlan and G.P. Rodnan, Effects of food, fast and alcohol on serum uric acid and acute attacks of gout. Am. J. Med. 42: 38 (1967)

    Article  PubMed  CAS  Google Scholar 

  4. T. Gibson, V. Rodgers, F. Court-Brown, H.A. Simmonds, Dietary intake of gout patients, Ann. Rheum. Dis. 40: 515 (1981)

    Article  Google Scholar 

  5. T.S.F. Yu, J.H. Sirota, L. Berger, M. Halpern, A.B. Gutman, Effect of sodium lactate infusion on urate clearance in man, Proc. Soc. Exp. Biol. Med. 96: 809 (1957)

    PubMed  CAS  Google Scholar 

  6. F. Delbarre, C. Auscher, H. Brouilhet, A. de Géry, A.tion de l’ethanol dans la goutte et sur le métabolisme de l’acide urique, Sem. H6p. Paris, 43: 659 (1967)

    CAS  Google Scholar 

  7. J. Grunst, J. Dietze, M. Wicklmayr, Effect of metabolic changes on uric acid production of human liver in: “Urolithiasis Research”, H. Fleisch, W.G. Robertson, L.H. Smith, W. Vahlinsiek, ed., Plenum Press, N. York (1976)

    Google Scholar 

  8. H.S. Diamond, R. Lazarus, D. Kaplan, D. Halbersam, Effect of urine flow rate on uric acid excretion in man, Arthritis Rheum. 15: 338 (1972)

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Guy’s Hospital, London, UK

    A. V. Rodgers, T. Gibson, H. A. Simmonds & P. Toseland

Authors
  1. A. V. Rodgers
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  2. T. Gibson
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  3. H. A. Simmonds
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  4. P. Toseland
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Editor information

Editors and Affiliations

  1. University of Nijmegen Faculty of Medicine, Nijmegen, The Netherlands

    Chris H. M. M. De Bruyn

  2. Guy’s Hospital Medical School, London, UK

    H. Anne Simmonds

  3. University of Vienna, Vienna, Austria

    Mathias M. Müller

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© 1984 Plenum Press, New York

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Rodgers, A.V., Gibson, T., Simmonds, H.A., Toseland, P. (1984). The Effect of Beer Ingestion on Plasma and Urine Uric Acid in Gout and Normouricaemic Subjects. In: De Bruyn, C.H.M.M., Simmonds, H.A., Müller, M.M. (eds) Purine Metabolism in Man-IV. Advances in Experimental Medicine and Biology, vol 165. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4553-4_64

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  • DOI: https://doi.org/10.1007/978-1-4684-4553-4_64

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4555-8

  • Online ISBN: 978-1-4684-4553-4

  • eBook Packages: Springer Book Archive

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