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Adeninephosphoribosyltransferase (APRT)-Activity in Patients with Nephrolithiasis or Renal Failure

  • P. Banholzer
  • W. Gröbner
  • W. Löffler
  • S. Reiter
  • N. Zöllner
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 165)

Abstract

The homozygous state of APRT-deficiency is associated with high urinary levels of 2, 8-dihydroxyadenine (2, 8-DHA) and may lead to nephrolithiasis and renal failure (Cartier and Barnet 1974; van Acker et al., 1977). Heterozygous patients are usually without symptoms (Fox et al., 1977). Recently Kuroda et al. (1981) reported of heterozygous patients with elevated 2, 8-DHA excretion and 2, 8-DHA stones.

Keywords

Renal Failure Uric Acid Kidney Stone Urologia Internat Unselected Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • P. Banholzer
    • 1
  • W. Gröbner
    • 1
  • W. Löffler
    • 1
  • S. Reiter
    • 1
  • N. Zöllner
    • 1
  1. 1.Medizinische PoliklinikUniversität MünchenMünchen 2Germany

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