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Renal Handling of Uric Acid in Normal Subjects: Its Behaviour with Respect to Different Filtered Loads

  • F. Mateos
  • J. G. Puig
  • E. Prieto
  • E. Herrero
  • A. Muñoz
  • J. Ortiz Vázquez
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 165)

Abstract

Serum uric acid concentration in man is the result of complex biosynthetic, catabolic, and excretory processes. Recent investigations of the urate transport system in the human kidney have provided evidence for a four-component model: glomerular filtration, presecretory reabsorption, tubular secretion, and postsecretory reabsorption1.

Keywords

Uric Acid Serum Uric Acid Tubular Reabsorption Tubular Secretion Renal Handling 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    H. S. Diamond, and J. S. Paolino, Evidence for a postsecretory reabsorptive site for uric acid in man, J. Clin Invest. 52: 1491 (1973).PubMedCrossRefGoogle Scholar
  2. 2.
    D. J. Levinson, and L. B. Sorensen, Renal handling of uric acid in normal and gouty subjects: evidence for a 4-component system, Ann. Rheum. Dis. 39: 173 (1980).PubMedCrossRefGoogle Scholar
  3. 3.
    A. de Vries, and O. Sperling, Inborn hypouricemia due to isolated renal tubular defect, Biomedicine, 30: 75 (1979).PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • F. Mateos
    • 1
  • J. G. Puig
    • 1
  • E. Prieto
    • 1
  • E. Herrero
    • 1
  • A. Muñoz
    • 1
  • J. Ortiz Vázquez
    • 1
  1. 1.Departments of Internal Medicine and Clinical BiopathologyCiudad Sanitaria La PazU. Autónoma, MadridSpain

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