Renal Handling of Uric Acid in Normal Subjects: Its Behaviour with Respect to Different Filtered Loads
Part of the
Advances in Experimental Medicine and Biology
book series (AEMB, volume 165)
Serum uric acid concentration in man is the result of complex biosynthetic, catabolic, and excretory processes. Recent investigations of the urate transport system in the human kidney have provided evidence for a four-component model: glomerular filtration, presecretory reabsorption, tubular secretion, and postsecretory reabsorption1.
KeywordsUric Acid Serum Uric Acid Tubular Reabsorption Tubular Secretion Renal Handling
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H. S. Diamond, and J. S. Paolino, Evidence for a postsecretory reabsorptive site for uric acid in man, J. Clin Invest
. 52: 1491 (1973).PubMedCrossRefGoogle Scholar
D. J. Levinson, and L. B. Sorensen, Renal handling of uric acid in normal and gouty subjects: evidence for a 4-component system, Ann. Rheum. Dis
. 39: 173 (1980).PubMedCrossRefGoogle Scholar
A. de Vries, and O. Sperling, Inborn hypouricemia due to isolated renal tubular defect, Biomedicine
, 30: 75 (1979).PubMedGoogle Scholar
© Plenum Press, New York 1984