Hyperuricemia in Primary Hyperparathyroidism: Incidence and Evolution after Surgery

  • José M. Castrillo
  • Manuel Díaz-Curiel
  • Aurelio Rapado
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 165)


Hyperuricemia was first found to be associated with primary hyperparathyroidism (PHP) by Mintz (1) in 1961. He detected it in 50 per cent of his patients. Later on Scott et al. (2) related the hyperuricemia mainly to renal failure, and also to a tubular disorder in nephrocalcinosis, a frequent finding in their PHP cases. Posterior series reported by Mallette (3) and Christensson (4) describe a high incidence of hyperuricemia in patients with PHP, a close relation between the levels of calcium and uric acid being observed. However no changes in the uricemia levels were seen after parathyroidectomy.


Uric Acid Serum Uric Acid Primary Hyperparathyroidism Serum Uric Acid Level Serum Urate 
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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • José M. Castrillo
    • 1
  • Manuel Díaz-Curiel
    • 1
  • Aurelio Rapado
    • 1
  1. 1.Unidad Metabólica, Fundación Jiménez DíazUniversidad AutónomaMadridSpain

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