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Prostaglandins and Immunoregulation

  • Bernard M. Jaffe
  • M. Gabriella Santoro
  • Peter Le Port
  • Cartesio Favalli
  • David Hofer
  • Enrico Garaci

Abstract

Although numerous recent studies have implicated prostaglandins in the control of the immune response, both suppressive and stimulatory effects have been reported. While our earlier studies dealing with transplantation suggested PGE compounds have potent immunosuppressive actions, our later studies, which have focused on tumor-bearing animals, have demonstrated that these compounds stimulate the immune response. This chapter will review our work on prostaglandins and immunoregulation and clarify this apparent paradox.

Keywords

Skin Allograft Numerous Recent Study Normal Mouse Control Skin Allograft Survival Potent Immunosuppressive Action 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Bernard M. Jaffe
    • 1
    • 2
  • M. Gabriella Santoro
    • 1
    • 2
  • Peter Le Port
    • 1
    • 2
  • Cartesio Favalli
    • 1
    • 2
  • David Hofer
    • 1
    • 2
  • Enrico Garaci
    • 1
    • 2
  1. 1.The Department of SurgeryS.U.N.Y. Downstate Medical CenterNew YorkUSA
  2. 2.The Institute of MicrobiologyUniversity of RomeRomeItaly

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