Thymic Factors in Experimental Diseases
As a series of methods were available for determination of serum thymic hormone-like activity (Bach and Dardenne, 1973; Astaldi et al., 1976; Lewis et al., 1981), studies were carried out by several researchers in order to determine modifications of thymic activity in different clinical and experimental conditions. This area of investigation has been considered of primary interest in the recent years for the following reasons:
understanding the pathogenesis of several diseases;
possibility of substitute therapy with thymic hormones;
contribution to a better knowledge of the pathophysiology of the thymus.
KeywordsCandida Albicans Mycosis Fungoides Thymic Epithelial Cell Experimental Disease Subacute sClerosing Panencephalitis
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- Bach, M.A., and Bach, J.F., 1974, in: “Prostaglandin Synthetase Inhibitors,” H.J., Robinson, and J.R., Vane, eds., Raven Press, New York, p. 241.Google Scholar
- Franceschi, C., Licastro, F., Chiricolo, M., Bonetti, F., Zannotti, M., Fabris, N., Mocchegiani, E., Fantini, M.P., Paolucci, P., and Masi, M., 1981, Deficiency of autologous mixed lymphocyte reactions and serum thymic factor level in Down’s syndrome, J. Immunol., 12:1261.Google Scholar
- Goldstein, A.L., Low, T.L.K., Adoo, M., Clure, J. Mc., Thurman, G.B., Rossio, G., Lay, C.Y., Chang, D., Wang-Su-Sun, Harwey, C., Ramel A.H., and Meienhofer, J., 1977, Thymosin α 1 isolation and sequence analysis of an immunologically active thymic polypeptide, Proc. Natl. Acad. Sci., USA, 74:725.PubMedCrossRefGoogle Scholar
- Hobbs, J.R., Byron, N.A., Campbell, M.A., Copeman, P.W.M., Gibbs, M., Lane, A.M., Perez, A., and Staughton, R.C.D., 1980, Thymosin-inducible lymphocytes in athopy, in: “Thymus, Thymic hormones and T lymphocytes,” Aiuti, F. and Wigzell, H., eds., Acad. Press, p. 143.Google Scholar
© Plenum Press, New York 1983