Differential Regulation of the Adh1 Gene in Maize: Facts and Theories
All genes are differentially regulated in the sense that each gene is expressed at different levels in different tissues and times during development and senescence. A gene that was expressed to the same extent in every cell at all times would be highly unusual: even such basic housekeeping genes as those specifying the histones are differentially regulated over the cell cycle. Tissue and temporal specificity is thus a fundamental property of genes in higher organisms.
KeywordsDifferential Regulation Reciprocal Effect Regulatory Mutant Allyl Alcohol Gene Competition
Unable to display preview. Download preview PDF.
- 5.Birchler, J.A., M. Alleman, and M. Freeling. 1981. The construction of a segmental tetrasomic line of maize. Maydica 26: 3–10.Google Scholar
- 10.Freeling, M. 1975. Further studies on the balance between Adhl and Adh2 in maize: Gene competitive programs. Genetics 82: 641–654.Google Scholar
- 12.Freeling, M., and J.A. Birchler. 1981. Mutants and variants of the alcohol dehydrogenase-1 gene in maize. In Genetic Engineering: Principles and Methods. J.K. Setlow and A. Hollaender, eds. Plenum Press, New York.Google Scholar
- 13.Freeling, M., D.S.-K. Cheng, and M. Alleman. 1982. Mutant alleles that are altered in quantitative, organ-specific behavior. Devel. Genet. (in press).Google Scholar
- 15.Gerlach, W.L., A.J. Pryor, E.S. Dennis, R.J. Ferl, M.M. Sachs, and W.J. Peacock. 1982. cDNA cloning and induction of the alcohol dehydrogenase gene (Adhl) of maize. Proc. Natl. Acad. Sci. USA 79: 2981–2985.Google Scholar
- 16.Kelley, P., and M. Freeling. 1982. A preliminary comparison of maize anaerobic and heat-shock proteins. In Induction of Heat Shock Protein, M.J. Schlesinger, A. Tissiers, and M. Ashburner, eds. Cold Spring Harbor, New York (in press).Google Scholar
- 19.Paigen, K. 1979. Genetic factors in developmental regulation. In Physiological Genetics. J.G. Scandalios, ed. Academic Press, New York.Google Scholar
- 26.Schwartz, D. 1976. Regulation of the alcohol dehydrogenase genes in maize. Stadler Genetics Symp. 8: 9–15.Google Scholar
- 28.Strommer, J.N., S. Hake, J. Bennetzen, W.C. Taylor, and M. Freeling. 1982. Regulatory mutants of the maize Adhl gene caused by DNA insertions. Nature (in press).Google Scholar
- 30.Woodman, J.C., and M. Freeling. 1981. Identification of a genetic element that controls the organ-specific expression of Adhl in maize. Genetics 98: 354–378.Google Scholar