Alterations in Circadian Secretion of Pituitary and Pineal Hormones in Affective Disorders

  • Julien Mendlewicz


Biological rhythms are an integral part of life. The day and night 24-hr period is present in almost all biological systems, remaining constant in various environments. This observation has led to the concept of endogenous biological clocks. The exact synchronization of the 24-hr period also involves external synchronizers (“Zeitgebers”). Besides circadian rhythms, living organisms also present shorter infradian rhythms such as the REM period of sleep (paradoxical sleep) or longer ultradian rhythms such as the menstrual cycle in female.


Circadian Rhythm Depressed Patient Depressive Illness Biological Rhythm Paradoxical Sleep 
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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • Julien Mendlewicz
    • 1
  1. 1.Department of Psychiatry, University Clinics of Brussels, Erasme HospitalFree University of BrusselsBrusselsBelgium

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