Psychoendocrinology of Depression

  • Gregory M. Brown
  • Paul Grof
  • Eva Grof


Despite continuing progress in the treatment and prophylaxis of affective disorders, mental depression remains a major world health problem. Statistics on mental depression vary to some extent; however, they all attest to the high frequency of this disorder in the population. The lifetime risk of any one of us suffering from a depression of clinical severity has been estimated at between 10 and 15% (Weissman and Klerman, 1978). According to recent WHO reports, at least one hundred million people are suffering from mental depression of clinical intensity at any time (Sartorius, 1979).


Depressed Patient Affective Disorder Biogenic Amine Growth Hormone Response Depressive Illness 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Gregory M. Brown
    • 1
  • Paul Grof
    • 2
  • Eva Grof
    • 3
  1. 1.Department of NeurosciencesMcMaster UniversityHamiltonCanada
  2. 2.Department of PsychiatryMcMaster University, and Hamilton Psychiatric HospitalHamiltonCanada
  3. 3.Department of PsychiatryMcMaster UniversityHamiltonCanada

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