Effects on Pavlovian Conditioning
  • D. A. Powell
  • Shirley L. Buchanan


The behavioral effects of a variety of hypothalamic neuropeptides have long been known (e.g., Applezweig and Baudry, 1955; Levine and Jones, 1965). Early experiments by de Wied and his colleagues (e.g., de Wied, 1965, 1969) revealed that adenohypophysectomy produced active avoidance deficits; others have shown that hypophysectomy also impairs passive avoidance behavior (e.g., Weiss et al., 1970). Later experiments revealed that the performance of these animals can be restored by treatment with ACTH peptide fragments with little or no adrenocortical effect, as reviewed recently by de Wied and Gispen (1977) and de Wied (1980).


Unconditioned Stimulus Classical Conditioning Pavlovian Conditioning Extinction Session Extinction Training 
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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • D. A. Powell
    • 1
  • Shirley L. Buchanan
    • 1
  1. 1.Neuroscience Laboratory, Wm. Jennings Bryan Dorn Veterans’ HospitalUniversity of South CarolinaColumbiaUSA

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