Relation of Neuroendocrine System to Reproductive Decline in Female Rats

  • Pierre Aschheim


The reproductive decline in female mammals is universal. Age-related sterility in rats is complete at about 15–17 months (Miller et al., 1979), when approximately 50–60% of the lifetime is spent. This type of sterility is multifactorial, the most important factor being senescence of the uterus. Oocyte alterations also occur. Disregarding these reproductive aspects, we will focus on aging of the hypothalamic-hypophysialovarian axis.


Luteinizing Hormone Estrous Cycle Luteinizing Hormone Surge Luteinizing Hormone Secretion Luteinizing Hormone Release 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Pierre Aschheim
    • 1
  1. 1.Unité de Recherches GérontologiquesINSERM U.118ParisFrance

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