Changes in Growth Hormone Secretion in Aging Rats and Man, and Possible Relation to Diminished Physiological Functions

  • William E. Sonntag
  • Lloyd J. Forman
  • Joseph Meites


Growth hormone (GH) is the most important protein-anabolic agent in the body and is essential for protein synthesis in body tissues throughout life. Growth hormone promotes body growth, bone growth, and liver, kidney, and hematopoietic functions. It stimulates the thymus gland that produces T cells and the hormone thymosin, which stimulates antibody production. Growth hormone also affects other physiological processes, including carbohydrate, lipid, vitamin, and mineral metabolism. The actions of GH appear to be mediated by direct action on tissues, and also through a family of hormones secreted by the liver, the somatomedins.


Growth Hormone Growth Hormone Secretion Human Growth Hormone Growth Hormone Release Pituitary Growth Hormone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • William E. Sonntag
    • 1
  • Lloyd J. Forman
    • 2
  • Joseph Meites
    • 1
  1. 1.Department of Physiology, Neuroendocrine Research LaboratoryMichigan State UniversityEast LansingUSA
  2. 2.Department of MedicineUniversity of Medicine and Dentistry of New JerseyCamdenUSA

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