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HLA-DR and Renal Transplantation

  • Peter J. Morris
  • Alan Ting

Abstract

The serological detection of leukocyte antigens in man began some 20 years ago. Their subsequent recognition as histocompatibility antigens led to immediate interest in the possible application of leukocyte typing and matching to improve renal allograft survival. In the late 1960s it became apparent that these leukocyte antigens could be grouped into two series of allelic antigens. The two series of the major histocompatibility complex (MHC) in man (designated HLA-A and -B) were shown to be genetically controlled by two loci on chromosome 6.

Keywords

Graft Survival Renal Allograft Mixed Lymphocyte Reaction Graft Survival Rate Hyperacute Rejection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Peter J. Morris
    • 1
  • Alan Ting
    • 1
  1. 1.Nuffield Department of SurgeryUniversity of Oxford, John Radcliffe HospitalOxfordUK

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