Genitourinary Problems in the Elderly

  • Stephen C. Jacobs
  • Joseph B. Murphy


The kidneys reach their maximum size in early adult life and then gradually shrink approximately 20% by age 70. The number of glomeruli also decrease such that by age 70, only 50 to 70% of the 800,000 to 1,000,000 present at birth remain. In addition, the basement membrane of the glomerulus thickens with aging and tubular surface area decreases. Renal loss is scattered throughout the kidney, but a disproportionate loss occurs among the juxtamedullary nephrons, perhaps explaining some of the loss of urinary concentrating ability in elderly subjects.1 These changes appear to occur as part of the normal aging process without the presence of other systemic diseases. Obviously, common disorders of the elderly, such as hypertension and diabetes, will superimpose significant renal disease on the normal aging kidney.


Prostatic Cancer Bladder Cancer Bone Metastasis Peritoneal Dialysis Prostatic Carcinoma 
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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Stephen C. Jacobs
    • 1
    • 2
  • Joseph B. Murphy
    • 3
  1. 1.Department of UrologyThe Medical College of WisconsinMilwaukeeUSA
  2. 2.Urology Section, Surgery ServiceWood Veterans Administration Medical CenterWoodUSA
  3. 3.Department of UrologyThe Medical College of WisconsinMilwaukeeUSA

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