Advertisement

Neurospora crassa: A Unique System for Studying Circadian Rhythms

  • Jerry F. Feldman
  • Jay C. Dunlap

Abstract

Progress in a particular field of biology has often been the result of the development of an organism or system especially well suited to research on that problem. The value of E. coli to molecular biology, the mammalian red blood cell to membrane biochemistry, and the oat coleoptile to plant physiology has been well-documented.

Keywords

Circadian Rhythm Circadian Clock Period Length Neurospora Crassa Temperature Compensation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Atkinson, D. E., 1968, The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers, Biochemistry 7:4030–4034.Google Scholar
  2. Atkinson, D. E., 1970, Adenine nucleotides as universal stoichiometric metabolic coupling agents, Advances in Enzyme Regulation, 19:207–219.Google Scholar
  3. Beavo, J. A., Rogers, N. L., Crofford, O. B., Hardman, J. G., Sutherland, E. W., and Newman, E. V., 1970, Effects of xanthine derivatives on lipolysis and on adenosine 3′,5′ monophosphate phosphodiesterase activity, Mol. Pharmacol. 6:597–603.Google Scholar
  4. Bitz, D. M., and Sargent, M. L., 1974, A failure to detect an influence of magnetic fields on the growth rate and circadian rhythm of Neurospora crassa, Plant Physiol. 53:154–157.Google Scholar
  5. Bonner, J. T., Hall, E. M., Noller, S., Oleson, F. B., Jr., Roberts, A. B., 1972, Synthesis of cyclic AMP and phosphodiesterase in various species of cellular slime molds and its bearing on Chemotaxis and differentiation, Dev. Biol. 29:402–409.Google Scholar
  6. Borst, P., Loos, J. A., Christ, E. J., and Slater, E. C., 1962, Uncoupling activity of long-chain fatty acids, Biochim. Biophys. Acta 62:509–518.Google Scholar
  7. Botstein, D., and Jones, E. W., 1969, Nonrandom mutagenesis of the Escherichia coli genome by nitrosoguanidine, J. Bacteriol. 98:847–848.Google Scholar
  8. Bowman, B. J., Mainzer, S. F., Allen, K. E., and Slayman, C. W., 1978, Effects of inhibitors on the plasma membrane and mitochondrial adenosine triphosphatases of Neurospora crassa, Biochim. Biophys. Acta 512:13–28.Google Scholar
  9. Brain, R. D., Freeberg, J., Weiss, C. V., and Briggs, W. R., 1977a, Blue-light induced absorbance changes in membrane fractions from corn and Neurospora, Plant Physiol. 59:948–952.Google Scholar
  10. Brain, R., Woodward, D. O., and Briggs, W. R., 1977b, Correlative studies of light sensitivity and cytochrome content in Neurospora crassa, Carnegie Inst. Wash. Yearbook 1976, pp. 295–299.Google Scholar
  11. Brandt, William H., 1953, Zonation in a prolineless strain of Neurospora, Mycologia 45:194–208.Google Scholar
  12. Briggs, W. R., 1976, The nature of the blue light photoreceptor in higher plants and fungi, in: Light and Plant Development (H. Smith, ed.), pp. 7–18, Butterworths, Boston.Google Scholar
  13. Brody, S., 1973, Circadian oscillations of pyridine nucleotide levels and ratios in Neurospora, Abstr., Ann. Mtg. Am. Soc. Microbiol., p. 38.Google Scholar
  14. Brody, S., 1981, Oligomycin-resistant mutations in the DCCD-binding protein of the mitochondrial ATPase affect the circadian rhythm of Neurospora, Fed. Proc. 40:1734.Google Scholar
  15. Brody, S., and Forman, L., 1980, Interactions between exogenous fatty acids and mitochondria in Neurospora crassa, Abstr., Ann. Mtg. Am. Soc. Microbiol., K185.Google Scholar
  16. Brody, S., and Harris, S., 1973, Circadian rhythms in Neurospora: spatial differences in pyridine nucleotide levels, Science 180:498–500.Google Scholar
  17. Brody, S., and Martins, S., 1973, Effects of morphological and auxotrophic mutations on the circadian rhythm of Neurospora crassa, Genetics 74:S31.Google Scholar
  18. Brody, S., and Martins, S. A., 1976, Circadian rhythms in Neurospora: the role of unsaturated fatty acids, in: The Molecular Basis of Circadian Rhythms (J. W. Hastings and H. G. Schweiger, eds.), pp. 245–246, Dahlem Konferenzen, Berlin.Google Scholar
  19. Brody, S., and Martins, S. A., 1979, Circadian rhythms in Neurospora crassa: effects of unsaturated fatty acids, J. Bacteriol. 137:912–915.Google Scholar
  20. Bunning, E., 1973, The Physiological Clock, Third Ed. Springer-Verlag, New York.Google Scholar
  21. Costantini, M. G., Sturani, E., Ghersa, P., and Alberghina, L., 1978, Effects of caffeine on RNA and protein synthesis in Neurospora crassa, Exp. Mycol. 2:366–376.Google Scholar
  22. Criddle, R. S., Edwards, T. L., Partis, M., and Griffiths, D. E., 1977, Association of pantothenic acid with a protein subunit of yeast mitochondrial ATPase, FEB S Lett. 84:278–282.Google Scholar
  23. Cummings, F. W., 1975, A biochemical model of the circadian clock, J. Theor. Biol. 55:455–470.Google Scholar
  24. Davis, R. H., and deSerres, F. J., 1970, Genetic and microbiological research techniques for Neurospora crassa, Methods Enzymol. 17A:79–143.Google Scholar
  25. Delmer, D. P., and Brody, S., 1973, Periodic changes in the energy charge state of a circadian rhythm mutant of Neurospora crassa, Abstr., Ann. Mtg. Am. Soc. Microbiol., p. 38.Google Scholar
  26. Delmer, D. P., and Brody, S., 1975, Circadian rhythms in Neurospora crassa: Oscillation in the level of an adenine nucleotide, J. Bacteriol. 121:548–553.Google Scholar
  27. Dharmananda, S., 1980, Studies on the circadian clock of Neurospora crassa: Light-induced phase shifting, Ph.D. Thesis, Univ. of Calif., Santa Cruz.Google Scholar
  28. Dharmananda, S. and Feldman, J. F., 1979, Spatial distribution of circadian clock phase in aging cultures of Neurospora crassa, Plant Physiol. 63:1049–1054.Google Scholar
  29. Dieckmann, C., 1980, Circadian rhythms in Neurospora crassa: a biochemical and genetic study of the involvement of mitochondrial mtabolism in periodicity, Ph.D. Thesis, Univ. of Calif., San Diego.Google Scholar
  30. Dieckmann, C., and Brody, S., 1979, Circadian rhythms in Neurospora: Oligomycin-re-sistant mutants, Abstr., Ann. Mtg. Am. Soc. Microbiol., p. 159.Google Scholar
  31. Dieckmann, C., and Brody, S., 1980, Circadian rhythms in Neurospora crassa: Oligomycin-resistant mutations affect periodicity, Science 207:896–898.Google Scholar
  32. Dunlap, J. C., and Feldman, J., 1982, Frq-7, a circadian clock mutant whose clock is insensitive to cycloheximide, Neurospora Newsletter 29:12.Google Scholar
  33. Edwards, D. L., and Unger, B. W., 1978, Nuclear mutations conferring oligomycin resistance in Neurospora crassa, J. Biol. Chem. 253:4254–4258.Google Scholar
  34. Elovson, J., 1975, Purification and properties of the fatty acid synthetase complex from Neurospora crassa, and the nature of the fas- mutation. J. Bacteriol. 124:524–533.Google Scholar
  35. Engelmann, W., and Schrempf, M., 1980, Membrane models of circadian rhythms, Photochem. Photobiol. 5:49–86.Google Scholar
  36. Feldman, J. F., 1967a, Biochemical and Physiological Studies on the Circadian Clock of Euglena, PhD Thesis, Princeton Univ., Princeton, New Jersey.Google Scholar
  37. Feldman, J. F., 1967b, Lengthening the period of a biological clock in Euglena by cycloheximide, an inhibitor of protein synthesis, Proc. Natl. Acad. Sci. USA 57:1080–1087.Google Scholar
  38. Feldman, J. F., 1975, Circadian periodicity in Neurospora: alteration by inhibitors of cyclic AMP phosphodiesterase, Science 190:789–790.Google Scholar
  39. Feldman, J. F., 1982, Genetic approaches to circadian clocks, Annu. Rev. Plant Physiol. 33:583–608.Google Scholar
  40. Feldman, J. F., and Atkinson, C. A., 1978, Genetic and physiological characteristics of a slow-growing circadian clock mutant of Neurospora crassa, Genetics 88:255–265.Google Scholar
  41. Feldman, J. F., and Hoyle, M. N., 1973, Isolation of circadian clock mutants of Neurospora crassa, Genetics 75:605–613.Google Scholar
  42. Feldman, J. F., and Hoyle, M. N., 1974, A direct comparison between circadian and non-circadian rhythms in Neurospora crassa, Plant Physiol. 53:928–930.Google Scholar
  43. Feldman, J. F., and Hoyle, M. N., 1976, Complementation analysis of linked circadian clock mutants in Neurospora, Genetics 82:9–17.Google Scholar
  44. Feldman, J. F., and Widelitz, R., 1977, Manipulation of circadian periodicity in cysteine auxotrophs of Neurospora crassa, Abstr., Ann. Mtg. Am. Soc. Microbiol, p. 125.Google Scholar
  45. Feldman, J. F., Gardner, G. F., and Denison, R. A., 1979, Genetic analysis of the circadian clock of Neurospora, in: Biological Rhythms and Their Central Mechanisms (M. Suda et al., eds.), pp. 57–66, North-Holland/Else vier Biomedical Press, Amsterdam.Google Scholar
  46. Francis, C. D., and Sargent, M. L., 1979, Effects of temperature perturbations on circadian conidiation in Neurospora, Plant Physiol. 64:1000–1004.Google Scholar
  47. Frelinger, J. G., Motulsky, H., and Woodward, D. O., 1976, Effects of chloramphenicol on the circadian rhythm of Neurospora crassa, Plant Physiol. 58:592–594.Google Scholar
  48. Gardner, G. F., and Feldman, J. F., 1980, The frq locus of Neurospora crassa: a key element in circadian clock organization, Genetics 96:877–886.Google Scholar
  49. Gardner, G. F. and Feldman, J. F., 1981, Temperature compensation of circadian periodicity in clock mutants of Neurospora crassa, Plant Physiol. 68:1244–1248.Google Scholar
  50. Gottlieb, D., and Shaw, P. D., 1970, Mechanism of action of antifungal antibiotics, Annu. Rev. Phytopath. 8:371–402.Google Scholar
  51. Grindle, M., 1973, Sterol mutants of Neurospora crassa: their isolation, growth characteristics, and resistance to polyene antibiotics, Mol. Gen. Genet. 120:283–290.Google Scholar
  52. Halaban, R., and Feldman, J. F., 1973a, Circadian periodicity in acetate nonutilizing mutants of Neurospora crassa, Neurospora Newsletter 20:20.Google Scholar
  53. Halaban, R., and Feldman, J. F., 1973b, An acetate-requiring mutant of Neurospora crassa with an unusual rhythmic growth pattern, Genetics 74:S104–105.Google Scholar
  54. Harding, R., 1974, The effect of temperature on photo-induced carotenoid biosynthesis in Neurospora crassa, Plant Physiol. 54:142–147.Google Scholar
  55. Hastings, J. W., 1960, Biochemical aspects of rhythms: phase shifting by chemicals, Cold Spring Harbor Symp. Quant. Biol. 25:131–140.Google Scholar
  56. Hastings, J. W., and Schweiger, H.-G. (eds), 1976, The Molecular Basis of Circadian Rhythms, Dahlem Konferenzen, Berlin.Google Scholar
  57. Henry, S. A., and Keith, A. D., 1971, Saturated fatty acid requirer of Neurospora crassa, J. Bacteriol. 106:174–182.Google Scholar
  58. Hochberg, M. L., and Sargent, M. L., 1974, Rhythms of enzyme activity associated with circadian conidiation in Neurospora crassa, J. Bacteriol. 120:1164–1175.Google Scholar
  59. Jacklet, J., 1981, Circadian timing by endogenous oscillators in the nervous system: toward cellular mechanisms, Biol. Bull. 160:199–227.Google Scholar
  60. Karakashian, M. W., and Hastings, J. W., 1963, The effects of inhibitors of macromolecular biosynthesis upon the persistent rhythm of luminescence in Gonyaulax, J. Gen. Physiol. 47:1–12.Google Scholar
  61. Klemm, E., and Ninnemann, H., 1979, Nitrate reductase—key enzyme in blue light promoted conidiation and absorbance change of Neurospora, Photochem. Photobiol. 29:629–632.Google Scholar
  62. Konopka, R., 1981, Genetics and development of circadian rhythms in invertebrates, in: Handbook of Behavioral Neurobiology (J. Aschoff, ed.), Vol. 4, pp. 173–181, Plenum Press, New York.Google Scholar
  63. Lakin-Thomas, P. L., and Brody, S., 1981, Circadian rhythms in Neurospora: Additive and non-additive gene interactions, J. Cell Biol. 91:20a.Google Scholar
  64. Lowry, O. H., Passonneau, J. V., Schultz, D. W., and Rock, M. K., 1961, The measurement of pyridine nucleotides by enzymatic cycling, J. Biol. Chem. 236:2746–2755.Google Scholar
  65. Martens, C. L., and Sargent, M. L., 1973, Circadian rhythms of nucleic acid metabolism in Neurospora crassa, J. Bacteriol. 177:1210–1215.Google Scholar
  66. Marzluf, G., 1981, Regulation of nitrogen metabolism and gene expression in fungi, Microbiol. Rev. 45:437–461.Google Scholar
  67. Mattern, D., and Brody, S., 1979, Circadian rhythms in Neurospora crassa: Effects of saturated fatty acids, J. Bacteriol. 139:977–983.Google Scholar
  68. Mattern, D. L., Forman, L. R., and Brody, S., 1982, Circadian rhythms in Neurospora crassa: A mutation affecting temperature compensation, Proc. Natl. Acad. Sci. USA 79:825–829.Google Scholar
  69. Means, A. R., and Dedham, J. R., 1980, Calmodulin: an intracellular calcium receptor, Nature 285:73–77.Google Scholar
  70. Mishra, N. C., 1977, Genetics and biochemistry of morphogenesis in Neurospora, Adv. Genet. 19:341–405.Google Scholar
  71. Nakashima, H., 1981, A liquid culture method for the biochemical analysis of the circadian clock of Neurospora crassa, Plant Cell Physiol. 22:231–238.Google Scholar
  72. Nakashima, H., 1982a, Effects of membrane ATPase inhibitors on light-induced phase shifting of the circadian clock in Neurospora crassa, Plant Physiol. 69:619–623.Google Scholar
  73. Nakashima, H., 1982b, Phase shifting of the circadian clock by diethylstilbestrol and related compounds in Neurospora crassa, Plant Physiol. 70:982–986.Google Scholar
  74. Nakashima, H., and Feldman, J. F., 1980, Temperature sensitivity of light-induced phase shifting of the circadian clock of Neurospora, Photochem. Photobiol. 32:247–252.Google Scholar
  75. Nakashima, H., and Fujimora, Y., 1982, Light-induced phase shifting of the carcadian clock in Neurospora crassa requires ammonium salts at high pH, Planta 155:431–436.Google Scholar
  76. Nakashima, H., Perlman, J., and Feldman, J. F., 1981a, Cycloheximide-induced phase shifting of the circadian clock of Neurospora, Am. J. Physiol. 241:R31–R35.Google Scholar
  77. Nakashima, H., Perlman, J., and Feldman, J. F., 1981b, Genetic evidence that protein synthesis is required for the circadian clock of Neurospora, Science 212:361–362.Google Scholar
  78. Nelson, R. E., Selitrennikoff, C. P., and Siegel, R. W., 1975, Mutants of Neurospora deficient in nicotinamide adenine dinucleotide (phosphate) glycohydrolase, J. Bacteriol. 122:695–709.Google Scholar
  79. Ninnemann, H., 1979, Photoreceptors for circadian rhythms, Photochem. Photobiol. Rev. 4:207–265.Google Scholar
  80. Ninnemann, H., and Klemm-Wolfgramm, E., 1980, Blue light controlled conidiation and absorbance change in Neurospora mediated by nitrate reductase, in: The Blue Light Syndrome (H. Senger, ed.), pp. 238–243, Springer, Berlin.Google Scholar
  81. Njus, D., Sulzman, F. M., and Hastings, J. W., 1974, Membrane model for the circadian clock, Nature 248:116–120.Google Scholar
  82. O’Farrell, P., 1975, High resolution two-dimensional electrophoresis of proteins, J. Biol. Chem. 250:4007–4021.Google Scholar
  83. Paietta, J., and Sargent, M. L., 1981, Photoreception in Neurospora crassa: correlation of reduced light sensitivity with flavin deficiency, Proc. Natl. Acad. Sci. USA 78:5573–5577.Google Scholar
  84. Paietta, J., and Sargent, M. L., 1982, Blue light responses in nitrate reductase mutants of Neurospora crassa, Photochem. Photobiol. 35:853–855.Google Scholar
  85. Paietta, J., and Sargent, M. L., 1983a, Modification of blue light photoresponses by riboflavin analogs in Neurospora crassa, Plant Physiol, (in press).Google Scholar
  86. Paietta, J., and Sargent, M. L., 1983b, Isolation and characterization of light insensitive mutants of Neurospora crassa, Genetics (in press).Google Scholar
  87. Pastan, I., 1972, Cyclic AMP, Sci. Am. 227:97–105.Google Scholar
  88. Pavlidis, T., Zimmerman, W. F., and Osborn, J., 1968, A mathematical model for the temperature effects on circadian rhythms,J. Theor, Biol. 18:210–221.Google Scholar
  89. Pendyala, L., Smyth, J., and Wellman, A. M., 1979, Nature of 6-methylpurine inhibition and characterization of two 6-methylpurine-resistant mutants of Neurospora crassa, J. Bacteriol. 137:248–255.Google Scholar
  90. Perkins, D. D., and Barry, E. G., 1977, The cytogenetics of Neurospora, Adv. Genet. 19:133–285.Google Scholar
  91. Perkins, D. D., Glassey, M., and Bloom, B. A., 1962, New data on markers and rearrangements in Neurospora, Am. J. Genet. Cytol. 4:187–205.Google Scholar
  92. Perlman, J., 1981, Physiological and biochemical studies of circadian rhythmicity in Neurospora crassa, Ph.D. Thesis, Univ. of Calif., Santa Cruz.Google Scholar
  93. Perlman, J., Nakashima, H., and Feldman, J. F., 1981, Assay and characteristics of circadian rhythmicity in liquid cultures of Neurospora crassa, Plant Physiol. 67:404–407.Google Scholar
  94. Pittendrigh, C. S., 1960, Circadian rhythms and the circadian organization of living systems, Cold Spring Harbor Symp. Quant. Biol. 25:159–184.Google Scholar
  95. Pittendrigh, C. S., 1967, Circadian systems. I. The driving oscillator and its assay in Dro-sophila pseudoobscur a, Proc. Natl. Acad. Sci. USA 58:1762–1767.Google Scholar
  96. Pittendrigh, C. S., 1974, Circadian oscillations in cells and the circadian organization of multicellular systems, in: The Neurosciences, Third Study Program (F. O. Schmidt and F. G. Worden, eds.), pp. 437–458, MIT Press, Cambridge.Google Scholar
  97. Pittendrigh, C. S., Bruce, V. G., Rosenzweig, N. S., and Rubin, M. L., 1959, A biological clock in Neurospora, Nature 184:169–170.Google Scholar
  98. Pittendrigh, C. S., and Caldarola, P. C., 1973, General homeostasis of the frequency of circadian oscillations, Proc. Natl. Acad. Sci. USA 70:2697–2701.Google Scholar
  99. Roeder, P. E., Sargent, M. L., and Brody, S., 1982, Circadian rhythms in Neurospora eras sa: oscillations in fatty acids, Biochemistry 21:4909–4916.Google Scholar
  100. Ross, E. M., and Gilman, A. G., 1980, Biochemical properties of hormone-sensitive adenylate cyclase, Annu. Rev. Biochem. 49:533–564.Google Scholar
  101. Rusak, B., 1979, Neural mechanisms for entrainment and generation of mammalian circadian rhythms, Fed. Proc. 38:2589–2595.Google Scholar
  102. Sargent, M. L., 1969, Response of Neurospora to various antibiotics and other toxic chemicals, Neurospora Newsletter 5:17.Google Scholar
  103. Sargent, M. L., and Briggs, W. R., 1967, The effects of light on a circadian rhythm of conidiation in Neurospora, Plant Physiol. 42:1504–1510.Google Scholar
  104. Sargent, M. L., and Kaltenborn, S. H., 1972, Effects of medium composition and carbon dioxide on circadian conidiation in Neurospora, Plant Physiol. 50:171–175.Google Scholar
  105. Sargent, M. L., and Woodward, D. O., 1969, Genetic determinants of circadian rhythmicity in Neurospora, J. Bacteriol. 97:861–866.Google Scholar
  106. Sargent, M. L., Briggs, W. R., and Woodward, D. O., 1966, The circadian nature of a rhythm expressed by an invertaseless strain of Neurospora crassa, Plant Physiol. 41:1343–1349.Google Scholar
  107. Sargent, M. L., Ashkenazi, I. E., Bradbury, E. M., Bruce, V. G., Ehret, C. F., Feldman, J. F., Karakashian, M. W., Konopka, R. J., and Mergenhagen, D., 1976, The role of genes and their expression: group report, in: The Molecular Basis of Circadian Rhythms (J. W. Hastings and H. G. Schweiger, eds.), pp. 295–310, Dahlem Konferenzen, Berlin.Google Scholar
  108. Schmit, J. C., and Brody, S., 1976, Biochemical genetics of Neurospora crassa conidial germination, Bacteriol. Rev. 40:1–41.Google Scholar
  109. Scott, W. A., 1976a, Biochemical genetics of morphogenesis in Neurospora, Annu. Rev. Microbiol. 30:85–104.Google Scholar
  110. Scott, W. A., 1976b, Adenosine 3′:5′-cyclic monophosphae deficiency in Neurospora crassa, Proc. Natl. Acad. Sci. USA 73:2995–2999.Google Scholar
  111. Scott, W. A., and Solomon, B., 1973, Cyclic 3′,5′-AMP phosphodiesterase of Neurospora crassa, Biochem. Biophys. Res. Commun. 53:1024–1030.Google Scholar
  112. Scott, W. A., and Solomon, B., 1975, Adenosine 3′,5′-cyclic monophosphate and morphology in Neurospora crassa: Drug-induced alterations,J. Bacteriol. 122:454–463.Google Scholar
  113. Sebald, W., Sebald-Athaus, M., and Wächter, E., 1977, Altered amino acid sequence of the DCCD-binding protein in the nuclear oligomycin-resistant mutant AP-2 from Neurospora crassa, in: Genetics and Biogenesis of Mitochondria (F. Kaudewitz, R. Schweyen, W. Bandlow, and K. Wolf, eds.), DeGruyter, Berlin.Google Scholar
  114. Selitrennikoff, C., Nelson, R. E., and Siegel, R. W., 1974, Phase-specific genes for macro-conidiation in Neurospora crassa, Genetics 78:679–690.Google Scholar
  115. Serna, L., and Stadler, D., 1978, Nuclear division cycle in germinating conidia of Neurospora crassa, J. Bacteriol. 136:341–351.Google Scholar
  116. Slayman, C. W., and Tatum, E. L., 1964, Potassium transport in Neurospora. I. Intracellular sodium and potassium concentrations, and cation requirements for growth Biochim. Biophys. Acta 88:578–592.Google Scholar
  117. Stadler, D. R., 1959, Genetic control of a cyclic growth pattern in Neurospora, Nature 184:170–171.Google Scholar
  118. Sussman, A. S., Lowry, R. J., and Durkee, T., 1964, Morphology and genetics of a periodic colonial mutant of Neurospora crassa, Am. J. Bot. 51:243–252.Google Scholar
  119. Sweeney, B. M., 1974, A physiological model for circadian rhythms derived from the Ace-tabularia rhythm paradoxes, Int. J. Chronobiol. 2:25–33.Google Scholar
  120. Sweeney, B. M., 1979, Bright light does not immediately stop the circadian clock of Gonyaulax, Plant Physiol. 64:341–344.Google Scholar
  121. Takahashi, J. S., and Menaker, M., 1979, Physiology of avian circadian pacemakers, Fed. Proc. 38:2583–2588.Google Scholar
  122. Taylor, W., and Feldman, J., 1982, Nutritional manipulation of circadian period length of auxotrophic mutants, Neurospora Newsletter 29:12.Google Scholar
  123. Terenzi, H. F., Flawia, M. M., and Torres, H. N., 1974, A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity, Blochem. Biophys, Res. Commun. 58:990–996.Google Scholar
  124. Turian, G., and Bianchi, D. E., 1972, Conidiation in Neurospora, Bot. Rev. 38:119–154.Google Scholar
  125. West, D. J., 1975, Effects of pH and biotin on a circadian rhythm of conidiation in Neurospora crassa, J. Bacteriol. 123:387–389.Google Scholar
  126. West, D. J., 1976, Phase shift of the circadian rhythm of conidiation in response to ultraviolet light, Neurospora Newsletter 23:17–18.Google Scholar
  127. Woodward, D. O., and Sargent, M. L., 1973, Circadian rhythms in Neurospora, in: Behaviour of Microorganisms (A. Perez-Miravete, ed.), pp. 282–296, Plenum Press, New York.Google Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Jerry F. Feldman
    • 1
  • Jay C. Dunlap
    • 1
  1. 1.Thimann LaboratoriesUniversity of CaliforniaSanta CruzUSA

Personalised recommendations