Skip to main content
SpringerLink
Log in

Psychoactive Drugs in Psychosomatic Medicine

  • Chapter
Psychosomatic Medicine

  • 139 Accesses

Abstract

When dealing with a patient who has a chronic or a life-threatening illness, physical illness receives utmost care but psychosomatic aspect very little. Thus, we speak of the “coronary” needing intensive care and the “psychosomatic” needing psychotherapy which in fact is responding to one part of the problem. The patient who suffers from a disease is neither psyche nor soma alone and will be grateful to you if he will derive benefit from a comprehensive therapy. The origin, perpetuation and treatment of psychosomatic illnesses are multifaceted. Focusing on one aspect of the problem to the exclusion of others is definitely not beneficial. I address myself primarily to the usefulness of psychoactive drugs in some of the physical disorders not to imply its exclusive value but to expose its synergestic value with other forms of therapy. In addition, the opposite problem, rather more serious, psychosomatic disorders secondary to psychoactive drug therapy will also be elucidated to impart the feeling that art of using the medication in the total treatment regime and not mere application is important.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Adler, R.H.: Psychotropic agents in the management of chronic pain. J. Human Stress 4; 13–17, 1978.

    Article  PubMed  CAS  Google Scholar 

  • Ananth, J.: Antiasthmatic effects of chrlorpromazine. Canad. Med. Assoc. J. 110; 1131, 1974.

    PubMed  Google Scholar 

  • Ananth, J. and Huapaya, L.: Depression associated with hypertension: a review. Psychiat. J. Univ. Ottawa 5; 58–62, 1980.

    Google Scholar 

  • Bradley, J.J.: Severe localized pain associated with the depressive syndrome. Brit. J. Psychiat. 109; 741–745, 1963.

    Article  PubMed  CAS  Google Scholar 

  • Chevenne, J.: Treatment of pain with a group of phenothiazine amines. La Presse Medicale 68; 2347-, 1960.

    Google Scholar 

  • Couch, J.R., Zeigler, D.K. and Hassanein, R.: Amitriptyline in the prophylaxis of migraine. Neurology 26; 121–127, 1976.

    PubMed  CAS  Google Scholar 

  • Crocket, J.A.: Chlorpromazine in asthma, chronic bronchitis and emphysema. Brit. J. Tuberculosis Dis. Chest 50; 221–224, 1956.

    Article  CAS  Google Scholar 

  • Csatary, L.K.: Cancer and chlorpromazine. Lancet. 2; 338–339, 1972.

    Article  PubMed  CAS  Google Scholar 

  • Dabbs, C.H. and Peirce, E.C.: Causalgiz treated with chlorpromazine hydrochloride. J.A.M.A. 159; 1626–1628, 1955.

    Article  CAS  Google Scholar 

  • Freyhan, F.A.: Loss of ejaculation during mellaril treatment. Amer. J. Psychiat. 118; 171–172, 1961.

    PubMed  CAS  Google Scholar 

  • Friedman, A.P.: The migraine syndrome. Bull. N.Y. Acad. Med. 44; 45–62, 1968.

    PubMed  CAS  Google Scholar 

  • Gardos, G. and Cole, J.O.: Weight reduction in schizophrenics by molindone. Amer. J. Psychiat. 134; 302–304, 1977.

    PubMed  CAS  Google Scholar 

  • Goldfarb, A.A. and Venutolo, F.: The use of an antidepressant drug in chronically allergic individuals. Ann. Allergy 21; 667676, 1963.

    Google Scholar 

  • Gomersall, J.D. and Stuart, A.: Amitriplyline in migraine prophylaxis. J. Neurol. Neurosurg. Psychiat. 36; 684–690, 1973.

    Article  PubMed  CAS  Google Scholar 

  • Gordon, R.A. and Campbell, M.: The use of chlorpromazine in intractable pain associated with terminal carcinoma. Canad. Med. Assoc. J. 75; 420–421, 1956.

    PubMed  Google Scholar 

  • Greer, S., Morris, T. and Pettingale, K.W.: Psychological response to breast cancer: effect on outcome. Lancet. 2; 785–787, 1979.

    Article  PubMed  CAS  Google Scholar 

  • Guy, R.: An essay on scirrous tumours and cancer. J & A Churchill: London, 1959.

    Google Scholar 

  • Hart, F.D.: The use of psychotropic drugs in rheumatology. J. Int. Med. Res. 4; 15–19, 1976.

    PubMed  CAS  Google Scholar 

  • Heller, J.: Another case of inhibition of ejaculation as side effect of mellaril. Amer. J. Psychiat. 118; 173–174, 1961.

    PubMed  CAS  Google Scholar 

  • Hill, R., Bell, C., Goldberg, H.: Effect of fluphenazine hydrochloride on R3230 A.C. mammary carcinoma and mammary glands of the rat. Cancer Res. 31; 1111–1127, 1971.

    Google Scholar 

  • Katz, J., Kunofsky, S., Patton, R.E.: Cancer mortality among patients in New York mental hospitals. Cancer 20; 2194–2199, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Kerr, T.A., Schapira, K. and Roth, M.: The relationship between premature death and affective disorder. Brit. J. Psychiat. 115; 1277–1282, 1969.

    Article  PubMed  CAS  Google Scholar 

  • Lance, J.W. and Curran, D.A.: Treatment of chronic tension headache. Lancet 2; 1236–1239, 1964.

    Article  Google Scholar 

  • Lasagna, L. and DeKornfeld, T.J.: Methotrimeprazine: a new phenothiazine derivative with analgestic properties. J.A.M.A. 178; 887–888, 1961.

    Article  PubMed  CAS  Google Scholar 

  • Lassman, P.L., Moody, J.F. and Gryspeerdt, G.L.: Central pain due to cerebral ischaemia. folia psychiatrica neurologica, et Neuroschiriargica Needlandica 62; 34–1959.

    Google Scholar 

  • Lee, R. and Spencer, P.S.J.: Antidepressants and pain: a review of the pharmacological data supporting the use of certain tricyclics in chronic pain. J. Inter. Med. Res. 5; 146–156, 1977.

    CAS  Google Scholar 

  • Lesse, S.: Masked depression–a diagnostic and therapeutic problem. Dis. Nerv. Syst. 29; 169–173, 1968.

    PubMed  CAS  Google Scholar 

  • Levij, I.S. and Polliak, A.: Inhibitions of chemical carcinogenesis in the hamster cheek pouch by topical chlorpromazine. Nature 228; 1096–1097, 1970.

    Article  PubMed  CAS  Google Scholar 

  • Lindsay, P.G. and Wyckoff, M.: The depression pain syndrome and its response to antidepressants. Psychosomatics 22; 571–577, 1981.

    PubMed  CAS  Google Scholar 

  • Mahloudji, M.: Prevention of migraine. Brit. Med. J. 1; 182–183, 1969.

    Article  PubMed  CAS  Google Scholar 

  • Mearles, R.A., Mills, J.E., Horvath, T.B., Atkinson, J.M., Pun, L.Q. and Rand, M.J.: Amitriptyline and asthma. Med. J. Aust. 2; 25–28, 1971.

    Google Scholar 

  • Merskey, H.:• Psychiatric patients with persistent pain. J. Psychosom. Res. 10; 383–387, 1967.

    Article  PubMed  Google Scholar 

  • Merskey, H. and Hester, R.A.: The treatment of chronic pain with psychotropic drugs. Postgrad. Med. J. 48; 594–598, 1972.

    Article  PubMed  CAS  Google Scholar 

  • Montilla, E., Frederick, W.S. and Cass, L.J.: Analgesic effect of methotrimeprazine and morphine: a clinical comparison. Arch. Int. Med. 111; 725, 1963.

    Article  Google Scholar 

  • Panaccio, V.: Trimeprazine: a new phenothiazine derivative for treatment of pruritic dermatoses. Canad. Med. Assoc. J. 80; 885–1959.

    Google Scholar 

  • Paoli, R., Darcourt, G. and Cossa, P.: Preliminary note on the action of imipramine in painful states. Rev. Neurol. 102; 503–1960.

    Google Scholar 

  • Paradis, B.: Analgesic and anaesthitic properties of levomepromazine (NO2INAN–7044RP). Canad. Anaesthetists Soc. J. 9; 153–1962.

    Google Scholar 

  • Pilowsky, I., Chapman, C.R. and Bonica, J.J.: Pain, depression and illness behavior in a pain clinic population. Pain 4; 183191, 1977.

    Google Scholar 

  • Pisciotta, A.V.: Agronulocytosis induced by certain phenothiazine derivaties. J.A.M.A. 208; 1862–1868, 1969.

    Article  PubMed  CAS  Google Scholar 

  • Pudov, V.I.: Effect of aminazine on metastatic dissemination of Brown-Pearce tumour. Farmikol Toksikol. 34; 454–456, 1971.

    CAS  Google Scholar 

  • Rassidakis, N.C., Kelleporis, M. and Fox, S.: Malignant neoplasma as a cause of death among psychiatric patients. Int. Ment. Health Res. Newsletter 13; 6, 1971. •

    Google Scholar 

  • Rassidakis, N.C., Kelleporis, M. and Karaiassefidis, K.: Malignant neoplasm as a cause of death among psychiatric patients. Int. Mental Health Res. Newsletter 14; 1–3, 1972.

    Google Scholar 

  • Robinson, K.C., Zuck, D.: Chlorpromazine in status asthmaticus. Lancet 1; 1349, 1954.

    Article  Google Scholar 

  • Sanger, M.D.: Psychosomatic allergy. Psychosomatics 11; 473–476, 1970.

    PubMed  CAS  Google Scholar 

  • Scott, W.A.M.: The relief of pain with an antidepressant in arthritis. Practioner 202; 802–807, 1969.

    CAS  Google Scholar 

  • Shader, R.I.: Sexual dysfunction associated with thioridazine hydrochloride. J.A.M.A. 188; 1007–1009, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Shader, R.I., Nahun, J.P. and DiMascio A.: Amenorrhea in psycho-tropic drug side effects. (Ed) R.I. Shaker & A. DiMascio, Baltimore, Williams & Wilkins, 1970.

    Google Scholar 

  • Sigwald, J., Bouttier, D. and Caille, F.: The treatment of herpes and post-herpetic pain. Study of the results obtained with levomepromazine. Therapie 14; 818–1959.

    Google Scholar 

  • Sigwald, J., Herbert H. and Quetin A.: The treatment of herpes and post-herpetic pain with phenothiazine derivatives. Semaine des hopitaux de Paris 33; 1137–1957.

    Google Scholar 

  • Singh, G. and Verma, H.C.: Drug treatment of chronic intractable pain in patients referred to a psychiatry clinic. J. Indian Med. Ass. 56; 341–345, 1971.

    PubMed  CAS  Google Scholar 

  • Singh, H.: Case of inhibition of ejaculation as side effect of mellaril. Amer. J. Psychiat. 117; 1041–1042, 1961.

    Google Scholar 

  • Snow, H.: Cancer and cancer process. J & A Churchill: London, 1893.

    Google Scholar 

  • Spear, F.G.: Pain in psychiatric patients. J. Psychosom. Res. 11; 187–193, 1967.

    Article  PubMed  CAS  Google Scholar 

  • Sternbach, R.A., Janowski, D.S., Huey, L.Y.: Effects of altering brain serotonin activity on human chronic pain. In Bonica J.J. (ed): Advances in pain research and therapy. New York. Raven Press. 1976. Vol. 1, pp. 601–606.

    Google Scholar 

  • Sughihara, H., Ishiara, K. and Noguchi, H.: Clinical experience with amitriptyline (tryptonol) in the treatment of bronchial asthma. Ann. Allergy 23; 422–1965.

    Google Scholar 

  • Surawicz, F.G., Brightwell, D.R., Weitzel, D.W. and Ekkehard, O.: Cancer, emotions and mental illness: the present state of understanding. Amer. J. Psychiat. 133; 1306–1309, 1976.

    PubMed  CAS  Google Scholar 

  • Taub, A.: Relief of postherpetic neurolgia with psychotropic drugs. J. Neurosurg. 39; 235–239, 1973.

    Article  PubMed  CAS  Google Scholar 

  • Taubel, D.E.: Mellaril: Ejaculation disorders. Amer. J. Psychiat. 119; 87–1962.

    Google Scholar 

  • Taylor, D.C.: The components of sickness: diseases, illnesses and predicaments. Lancet 2; 1008–1010, 1979.

    Article  PubMed  CAS  Google Scholar 

  • Tyber, M.A.: Treatment of painful shoulder syndrome with amitriptyline and lithium carbonate. Canad. Med. Assoc. J. 111; 137140, 1974.

    Google Scholar 

  • Varsamis, J., Zuckhowski, T. and Maini, K.K.: Survival rates of death in geriatric psychiatric patients: a six year follow-up. Canad. Psychiat. Assoc. J. 7; 17–22, 1972.

    Google Scholar 

  • Von Knorring, L.: The experience of pain in depressed patients. Neuropsychobiology 1; 155–165, 1975.

    Article  PubMed  CAS  Google Scholar 

  • Ward, N.G., Bloom, V.L. and Friedel, R.O.: The effectiveness of tricyclic antidepressants in the treatment of co-existing pain and depression. Pain 7; 331–341, 1979.

    Article  PubMed  CAS  Google Scholar 

  • Watson, C.G. and Schuld, D.: Psychosomatic factors in the etiology of neoplasms. J. Consultative and Clinical Psycholosy 45; 455–464, 1977.

    Article  CAS  Google Scholar 

  • Webb. H.E. and Larscelles, R.G.: Treatment of facial and head pain associated with depression. Lancet 1; 355–356, 1962.

    Google Scholar 

  • Whitlock, F.A. and Siskind, M.: Depression and cancer: a followup study. Psychol. Med. 9; 747–752, 1979.

    Article  PubMed  CAS  Google Scholar 

  • Wilson, R.C.D.: Antiasthmatic effect of amitriptyline. Canad. Med. Assoc. J. 111; 212, 1974.

    PubMed  CAS  Google Scholar 

  • Woodforde, J.M., Dwyer, B., McEwen, B.W.: Treatment of postherpetic neurolgia. Med. J. Australia 2; 869–872, 1965.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychiatry Psychopharmacology Unit, University of California, Los Angeles Harbor-U.C.L.A. Medical Center, Torrance, California, USA

    J. Ananth

Authors
  1. J. Ananth
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Psychosomatic Service and Research, Champlain Valley Physicians, Hospital Medical Center, 12901, Plattsburgh, New York, USA

    Adam J. Krakowski M.D. (Chief) (Chief)

  2. Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, 950 East 59th Street, Chicago, Illinois, USA

    Chase Patterson Kimball M.D. (Professor of Psychiatry and Medicine) (Professor of Psychiatry and Medicine)

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Plenum Press, New York

About this chapter

Cite this chapter

Ananth, J. (1983). Psychoactive Drugs in Psychosomatic Medicine. In: Krakowski, A.J., Kimball, C.P. (eds) Psychosomatic Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4496-4_88

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-4496-4_88

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4498-8

  • Online ISBN: 978-1-4684-4496-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation