A Canine Model of Psychopathology

  • William G. Reese
  • Joseph E. O. Newton
  • Charles Angel


Periodically, under external, non-scientific pressure for “relevance,” we have proposed that the Arkansas Line of Nervous Pointer Dogs may be a suitable model of human psychopathology (1) or even of more specific human disorders such as anxiety or phobia (2, 3) or schizophrenia, especially catatonic (4). G. R. Smith, Jr., of our institution, sees strong parallels with the conservation-withdrawal phenomena of Engel and Schmale (5). Perhaps this paper should be entitled “a dog hunting a model.” Mlany of our past papers are referenced in the summary articles cited above and more recently by L. Lucas, et al., (6). Rather than burden this paper with a long bibliography, we refer the interested reader to the specific references cited (1, 3, 6). Statements of fact are backed up by experiments reported in the primary papers.


Canine Model Tonic Immobility Conflicting Stimulus Catatonic Schizophrenia Past Paper 
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  1. 1).
    Reese, W. G.: 1979. A dog model for human psychopathology. Am. J. Psychiatry, 136: 1168–1172.PubMedGoogle Scholar
  2. 2).
    Newton, J. E. O., Murphree, O. D., Kykman, R. A.: 1970. Sporadic transient atrioventricular block and slow heart rate in nervous pointer dogs. Pavlov J. Biol Sci 5: 75–89.Google Scholar
  3. 3).
    Dykman, R. A., Reese, W. G.: 1979. Familial anthropophobia in pointer dogs? Arch. Gen Psychiatry 36: 988–993.CrossRefGoogle Scholar
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    Peters, J. E., Murphree, O. D., Dykman, R. A.: 1967. Genetically-determined abnormal behavior in dogs. Pavlov J. Biol. Sci. 2: 206–215.Google Scholar
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  6. 6).
    Lucas, L. A., DeLuca, D. C., Newton, J. E. O., Angel, C. A.: 1980. Animal models for human psychopathology, in Gershon ES, Matthysse S., Breakfield 10, Ciaranello RD (eds): Genetic Research Strategies for Psychobiology and Psychiatry, pp. 241–252. The Boxwood Press.Google Scholar
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    Walls, R. G., Murphree, 0.D., Angel, C.A., Newton, J.E.O.: 1976. A multivariate discriminant analysis of behavioral measures in genetically nervous dogs. Pavlov J Biol Sci 11: 175–179.Google Scholar
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    Gantt, W.H.: 1944. Experimental Basis of Neurotic Behavior. Harper & Row Book Company, New York.Google Scholar
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    Peters, J.E.: 1966. Typology of dogs by the conditional reflex method. Pavlov J Biol Sci 1: 235–250.Google Scholar
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    Angel, C., Newton, J. E. 0., Reese, W. G.: Assessment of Pointer dog behavior. Pavlov J. Biol. Sci. 17: 84–88, 1982PubMedGoogle Scholar
  19. 19).
    Reese, W. G., Newton, J. E. 0., Angel, C.: Induced immobility in nervous and normal Pointer dogs. J. Nerv. Ment. Dis. 170: 605–613, 1982.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • William G. Reese
    • 1
  • Joseph E. O. Newton
    • 2
  • Charles Angel
    • 1
  1. 1.Department of Psychiatry and Behavioral SciencesUniversity of Arkansas for Medical SciencesLittle RockUSA
  2. 2.Department of Psychiatry and Behavioral Sciences, North Little Rock DivisionUniversity of Arkansas for Medical Sciences, and Veterans Administration Medical CenterUSA

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