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Stretch-Induced Transparency Change Associated with Cross-Bridge Deformation in Active Frog’s Muscle

  • F. W. Flitney
  • J. C. Eastwood
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 59)

Abstract

In a recent study of the transparency changes produced by stretching active frog’s muscle (Flitney & Eastwood, 1982), we identified a component of the optical signal which was associated with the extra tension generated. This was referred to as the tension-dependent transparency change, or TDC, to distinguish it from another component which appeared to be related to the change in muscle length. The amplitude of the TDC was found to vary linearly with the tension increment, Δ P, when this was made to change by altering the rest length of the muscle prior to stimulation. Since muscle stiffness (and hence, Δ P) depends upon the extent of filament overlap (see Discussion), this observation suggested to us that the TDC is generated by strain in the cross-bridges. However, for various reasons we could not exclude the possibility that the filaments themselves might be partially (or even wholly) responsible.

Keywords

Muscle Length Elastic Element Sarcomere Length Laser Light Scattering Muscle Stiffness 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Flitney, F.W. & Hirst, D.G., 1978. Cross-bridge detachment and sarcomere ‘give’ during stretch of active frog’s muscle. J. Physiol., 276: 449–465.Google Scholar
  2. Flitney, F.W. & Hirst, D.G., 1978a. Filament sliding and energy stored by the cross-bridges in active muscle subjected to cyclical length changes. J. Physiol. 276: 467–479.Google Scholar
  3. Flitney, F.W. & Eastwood, J.C., 1982. Transparency changes associated with force enhancement during stretch of active frogs’ muscle. In: Biomedical applications of laser light scattering. Elsevier/North - Holland Biomedical Press.Google Scholar
  4. Huxley, A.F. & Simmons, R.M. 1973. Mechanical transients and origin of muscular force. Cold Spring Harb. Symp. Quant. Biol., 37: 669–680.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • F. W. Flitney
    • 1
  • J. C. Eastwood
    • 1
  1. 1.Department of Physiology & Pharmacology Bute Medical BuildingUniversity of St AndrewsSt AndrewsScotland

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