Structure and Dynamics of Disk Membrane Vesicles

Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 59)


This paper has a simple objective. It is to show that the laser light scattering techniques constitute the crucial parts of a battery of physical methods employed to probe an interesting and important problem, i.e., the molecular mechanism of vertebrate photoreceptor function. In order to do so, I will first describe briefly what is known about the photoreceptor function of rod cells of the vertebrate retina. That will be followed by the description and justification for focusing on a particular organelle of a rod cell, i.e., disk membrane, and how we isolate them into vesicles in vitro and characterize their size and shape. Subsequently four specific studies with these vesicles that are relevant to the molecular mechanism of photoreception will be chosen to illustrate the point.


Surface Charge Density Disk Membrane Hypotonic Medium Bleached State Translational Diffusion Coefficient 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Hyuk Yu
    • 1
  1. 1.Department of ChemistryUniversity of WisconsinMadisonUSA

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