Investigation of Pesticide Metabolites in the Human

  • C. V. Eadsforth
Part of the Methodological Surveys in Biochemistry and Analysis book series (MSBA, volume 12)


In pesticide manufacture and usage, human exposure is minimized at every stage. The need to monitor this is the main impetus to the study of pesticide metabolism in man. That of selected pesticides, initially in animals, has been studied as part of industrial hygiene research programmes to indicate the most suitable analytical methods for monitoring exposure. These typically entail GC-ECD, and their development is in general based on a common major urinary metabolite or on the pesticide itself. Dose-excretion studies enable assays to be made on manufacturing operatives, formulators and sprayers.


Urinary Metabolite Aromatic Hydroxylation Triethyl Phosphate Main Impetus Dimethyl Phosphate 


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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • C. V. Eadsforth
    • 1
  1. 1.Sittingbourne Research CentreShell Research Ltd.Sittingbourne, KentUK

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