Modulation of Effector Lymphokines
As is now well known, lymphokines are soluble, non-antibody mediators produced by appropriately stimulated lymphocytes. They play important afferent roles with respect to enhancement or suppression of the induction of immunity. They are important in efferent reactions as well. These effector lymphokines, initially described in terms of in vitro bioassays, have been demonstrated in a variety of in vivo situations and, when exogenously administered, have been shown to exert profound effects in vivo (reviewed in 1).
KeywordsMigration Inhibition Factor Macrophage Migration Inhibition Factor Mitogenic Factor Desensitize State Lymphokine Production
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