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Antibody-Independent Mechanisms in the Development of Acquired Immunity to Malaria

  • William P. Weidanz
  • James L. Grun
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 162)

Abstract

The plasmodia are hemoprotozoan parasites which cause malaria in a variety of animal species, including man. Infection with these parasites stimulates acquired immune responses which are directed primarily against blood stages and, when successful, bring about a reduction in the number of circulating plasmodia and/or protect the host against reinfection with homologous parasites (1,2). While the actual mechanisms of resistance are ill-defined, it appears that immunity to malaria requires the participation of both T and B lymphocyte systems.

Keywords

Nude Mouse Acute Infection Deficient Mouse Intact Mouse Challenge Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • William P. Weidanz
    • 1
  • James L. Grun
    • 1
  1. 1.The Malaria Research Unit, Department of Microbiology and ImmunologyHahnemann Medical College and HospitalPhiladelphiaUSA

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