Cardiovascular Toxicity of Ionophores Used as Feed Additives

  • Berton C. Pressman
  • Mohammad Fahim
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 161)


Formidable quantities of microbial metabolites belonging to the class of ionophores are currently being fed to poultry and cattle raised for human consumption. Most fryers and broilers in the United States received 120 ppm monensin in their feed to control coccidiosisl while beef cattle are fed 30 ppm monensin which, possibly by exerting a favorable effect on the flora of the rumen,2 promotes a more efficient fermentation of cellulose and subsequent conversion of feed to meat.3


Hexane Extract Coronary Vasodilatation Cardiovascular Toxicity Microbial Metabolite Isolate Rabbit Heart 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Berton C. Pressman
    • 1
  • Mohammad Fahim
    • 1
  1. 1.Department of PharmacologyUniversity of MiamiMiamiUSA

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