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Basic Biology of New Developments in Biotechnology pp 63–76Cite as

Correction of Inborn Errors of Metabolism by Bone Marrow Transplant

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Abstract

A new development in medicine is the utilization of bone marrow transplantation for correction of inborn errors of metabolism. In the past, bone marrow transplantation had been utilized for the curative treatment of aplastic anemia, leukemia, neuroblastoma, and congenital immune and hematologic deficiencies. The fullest explanation of the potential for bone marrow transplant in the correction of inborn errors of metabolism has been outlined by Hobbs [8]. The final indication of the usefulness of this new development awaits case by case analysis. This review will illustrate the biological basis for the use of bone marrow transplant for correction of inborn errors of metabolism.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, 55455, USA

    William Krivit

Authors
  1. William Krivit
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Editors and Affiliations

  1. Associated Universities, Inc., Washington, D.C., USA

    Alexander Hollaender

  2. Exxon Research and Engineering Co., Linden, New Jersey, USA

    Allen I. Laskin

  3. University of Minnesota Medical School, Minneapolis, Minnesota, USA

    Palmer Rogers

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© 1983 Plenum Press, New York

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Krivit, W. (1983). Correction of Inborn Errors of Metabolism by Bone Marrow Transplant. In: Hollaender, A., et al. Basic Biology of New Developments in Biotechnology. Basic Life Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4460-5_5

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  • DOI: https://doi.org/10.1007/978-1-4684-4460-5_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4462-9

  • Online ISBN: 978-1-4684-4460-5

  • eBook Packages: Springer Book Archive

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