Correction of Inborn Errors of Metabolism by Bone Marrow Transplant
A new development in medicine is the utilization of bone marrow transplantation for correction of inborn errors of metabolism. In the past, bone marrow transplantation had been utilized for the curative treatment of aplastic anemia, leukemia, neuroblastoma, and congenital immune and hematologic deficiencies. The fullest explanation of the potential for bone marrow transplant in the correction of inborn errors of metabolism has been outlined by Hobbs . The final indication of the usefulness of this new development awaits case by case analysis. This review will illustrate the biological basis for the use of bone marrow transplant for correction of inborn errors of metabolism.
KeywordsBone Marrow Transplant Kupffer Cell Aplastic Anemia Chronic Granulomatous Disease Inborn Error
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