Human Immune Interferon (IFN-γ) Gene Sequence and Structure

  • Patrick W. Gray
  • David V. Goeddel
Part of the Basic Life Sciences book series


Human IFN-γ is encoded by a single gene which, in contrast to the IFN-α and IFN-β genes, contains three introns. This gene has been isolated from a recombinant human-λ gene library, and the entire gene and 5′ and 3′ flanking regions have been sequenced. Southern hybridizations failed to show any polymorphism of the gene or its flanking regions. The first intron contains a repetitive element which is unrelated to the Alu family repeat.


Human Leukocyte Interferon HpaII Site Human Fibroblast Interferon Code Region Probe Human Immune Interferon 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Patrick W. Gray
    • 1
  • David V. Goeddel
    • 1
  1. 1.Department of Molecular BiologyGenentech, Inc.South San FranciscoUSA

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