Drugs and Antibiotics: An Overview Chairman’s Comments
Biotechnology provides exciting new approaches for the discovery and production of novel biologically active molecules. This technology is applicable to numerous stages involved in the discovery and development of new drugs. Drug discovery is a complex process requiring a diverse group of scientific talents. In general, the process starts with a proposal for the intervention in the course of a specific disease. The initial idea is followed by a period of exploratory research, culminating in the identification of a chemical compound with the desired biological activity. The active chemical is then further investigated in preclinical testing, toxicology, and clinical studies. If the biological activity is confirmed and the compound has an adequate margin of safety, then a manufacturing process is developed. Drug discovery is a labyrinth of hidden problems which must be resolved in order to achieve successful marketing of a new drug.
KeywordsDrug Discovery Subunit Vaccine Exploratory Research Preclinical Testing Adequate Margin
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