Advertisement

Surface Antigens on Normal and Malignant Lymphoid Cells

  • Laurence Boumsell
  • Alain Bernard
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 57)

Abstract

We shall first briefly review the reactivity on normal lymphoid cells of various monoclonal antibodies we have used to study malignant tumor cell populations. We then emphasize the most important technical requirements for assessing the reactivity of MA with cell surfaces. Finally we report our results from the investigation of 66 cases of T-cell malignancy and of 111 cases of B and non-B, non T cell malignancies.

Keywords

Chronic Lymphocytic Leukemia Acute Lymphoblastic Leukaemia Antigenic Determinant Tumor Cell Population Indirect Immunofluorescence Assay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bernard A., & Boumsell L. (1981) in preparationGoogle Scholar
  2. 2.
    McMichael A. J., Pilch J.R., Galfre G., Mason D.Y., Fabre J.W. & Milstein C. (1979) Eur. J. Immunol. 9, 205–210CrossRefGoogle Scholar
  3. 3.
    Reinherz E.L., Kung P.C., Goldstein G., Levy R.H. & Schlossman S.F. (1980) Proc. Natl. Acad. Sci. USA 77: 1588–1592.CrossRefGoogle Scholar
  4. 4.
    Boumsell L. & Bernard A. (1981) in preparationGoogle Scholar
  5. 5.
    Kamoun M., Martin P.J., Hansen J.A., Brown M.A., Siadak A.W. & Nowinski R.C.J. (1981) J. EXp. Med. 153, 207–212CrossRefGoogle Scholar
  6. 6.
    Bernard A., Coppin H., Clausse M., Bayle C., Degos L., Valensi F. Flandrin G., Dausset J., Lemerle J. Boumsell L. 4th Int. Congr. Immunology 1980, Paris. Abstract Book (eds. J.L. Preud’homme V.A.L. Hawken) Abs. No. 18. 4. 07Google Scholar
  7. 7.
    Kung P.C., Goldstein G., Reinherz E.L. & Schlossman S.F. (1979) Science 206, 397–399.CrossRefGoogle Scholar
  8. 8.
    Hansen J.A., Martin P.J. & Nowinski R.C. (1980) Immunogenetics, 10, 247–260CrossRefGoogle Scholar
  9. 9.
    Reinherz E.L., Kung P.C., Goldstein G. & Schlossman S.F. (1979) Proc. Natl. Acad. Sci. USA 76, 4061–4065CrossRefGoogle Scholar
  10. 10.
    Haynes B.F., Eisenbarth G.S. & Fauci A.S. (1979) Proc. Natl. Acad. Sci. USA 76, 5829–5833CrossRefGoogle Scholar
  11. 11.
    Ledbetter J.A., Evans R.L., Lipinski M., Rundles C., Good R.A. & Herzenberg L.A. (1981) J. Exp. Med. 153, 310–323CrossRefGoogle Scholar
  12. 12.
    Evans R.L., Wall D.W., Platsoucas C.D., Siegal F.P., Fibrig F.M., Testa C.M. & Good R.A. (1981) Proc. Natl. Acad. Sci. 78: 544–548CrossRefGoogle Scholar
  13. 13.
    Reinherz E.L., Kung P.C., Goldstein G. & Schlossman S.F. (1980) J. Immunol. 124, 1301–1307Google Scholar
  14. 14.
    Stashenko P., Nadler L.M., Hardy R. & Schlossman S.F. (1980) J. Immunol. 125, 1678–1685Google Scholar
  15. 15.
    Nadler L.M., Stashenko P., Hardy R., Van Agthoven A., Terhorst C, & Schlossman S.F. (1981) J. Immunol, (in press)Google Scholar
  16. 16.
    Martin P.J., Hansen J.A., Nowinski R.C. & Brown M.A. (1981) Immunogenetics 11, 429–439Google Scholar
  17. 17.
    Royston E., Majda J.A., Baird S.M., Meserve B.L. & Griffiths J.C. (1979) Blood 54 (suppl. 1) 106 AGoogle Scholar
  18. 18.
    Engleman E.G., Warnke R., Fox R.I. & Levy R. (1981) in pressGoogle Scholar
  19. 19.
    Wang C.Y., Good R.A., Ammirati P., Dimbort G. & Evans R.L. (1980) J. Exp. Med. 151, 1539–1544CrossRefGoogle Scholar
  20. 20.
    Boumsell L., Coppin H., Pham D., Raynal B., Lemerle J., Dausset J. & Bernard A. (1980) J. Exp. Med. 152, 229–234CrossRefGoogle Scholar
  21. 21.
    Reinherz E.L., Kung P.C., Goldstein G. & Schlossman S.F. (1979) J. Immunol. 123, 1312–1317Google Scholar
  22. 22.
    Levy R., Dilley J., Fox R.I. & Warnke R. (1979) Proc. Natl. Acad. Sci. USA 76, 6552–6556CrossRefGoogle Scholar
  23. 23.
    Eisenbarth G.S., Haynes B.F., Schoer J,A. & Fauci A.S. (1980) J. Immunol. 124, 1237Google Scholar
  24. 24.
    Reinherz E.L., Kung P.C., Pesando J.M., Ritz J., Goldstein G, & Schlossman S.F. (1979) J. Exp. Med. 150, 1472–1482CrossRefGoogle Scholar
  25. 25.
    Ritz J., Pesando J.M., McConarty J.N., Lazarus H. & Schlossman S.F. (1980) Nature 283, 583–585CrossRefGoogle Scholar
  26. 26.
    Coppin, H., Boumsell L., Pham D. & Bernard A. (1981) in preparationGoogle Scholar
  27. 27.
    Van Wauke J.P., Demey J.R., & Goossens J.G. (1980) J. Immunol. 124, 2708–2713Google Scholar
  28. 28.
    Reinherz E.L., Hussey R.E. & Schlossman S.F. (1980) Europ. J. Immunol. 10, 758–762CrossRefGoogle Scholar
  29. 29.
    Cantor H. & Boyse E.A. (1975) J. Exp. Med. 141, 1390–1398CrossRefGoogle Scholar
  30. 30.
    Boumsell L., Richard Y., & Bernard A. in preparationGoogle Scholar
  31. 31.
    Boumsell L., Bernard A., Lepage V., Degos L., Lemerle J. & Dausset J. (1978) Europ. J. Immunol. 8, 900–904CrossRefGoogle Scholar
  32. 32.
    Brouet J.C., Valensi F., Daniel M.T., Flandrin G., Preud’homme J.L. & Seligmann M. (1976) Brit. J. Hameat. 33, 319–328CrossRefGoogle Scholar
  33. 33.
    Haynes B.F., Hemler M.E., Mann D.L., Eisenbarth G.S., Shelhamer J., Mostowski H.S., Thomas C.A., Strominger J.L. & Fauci A.S. (1981) J. immunol. in pressGoogle Scholar
  34. 34.
    Charron D.J., & McDevitt H.O. (1979) Proc. Natl. Acad. Sci. USA 76, 6567–6571CrossRefGoogle Scholar
  35. 35.
    Murphy D.B., Herzenberg L.A., Okumura K., Herzenberg L.A., & McDevitt H.O. (1976) J. Exp. Med. 144, 699–712CrossRefGoogle Scholar
  36. 36.
    Bonner W.A., Hulett H.R., Sweet R.G. & Herzenberg L.A. (1972) Rev. Scientific Instr. 43, 404–414CrossRefGoogle Scholar
  37. 37.
    Lebien T.W. & Kersey J.H. (1980) J. Immunol. 125, 2208–2214Google Scholar
  38. 38.
    Bernard A., Boumsell L., Bayle C., Richard Y., Coppin H., Penit C., Rouget P., Micheau C., Clausse B., Gerard-Marchant R., Dausset J. & Lemerle J. (1979) Blood 54, 1058–1068Google Scholar
  39. 39.
    Murphy S.B. (1978) N. Egl. J. Med. 299, 1446–1448CrossRefGoogle Scholar
  40. 40.
    Bernard A., Boumsell L., Reinherz E.L., Nadler L.M., Ritz J., Coppin H., Richard Y., Valensi F., Flandrin G., Dausset J. Lemerle J. & Schlossman S.F. (1981) Blood (in press)Google Scholar
  41. 41.
    Boumsell L., Bernard A., Reinherz E.L., Nadler L.M., Ritz J., Coppin H., Richard Y., Dubertret L., Degos L., Lemerle J. Flandrin G., Dausset J. & Schlossman S.F. (1981) Blood, 57, 526–531Google Scholar
  42. 42.
    Broder S., Edelson R.L., Lutzner M.A., Nelson D.L., MacDermott R.P., Durm M.E., Goldman C.K., Meade B.D. & Waldmann T.A. (1976) J. Clin. Invest. 58, 1297–1306CrossRefGoogle Scholar
  43. 43.
    Yoshida T., EDelson R., Cohen S. & Green I. (1975) J. Immunol. 114, 915–918Google Scholar

Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Laurence Boumsell
    • 1
  • Alain Bernard
    • 2
  1. 1.INSERM U93Hôpital Saint-LouisParisFrance
  2. 2.Laboratoire d’Immunologie des Tumeurs de l’EnfantInstitut Gustave RoussyVillejuifFrance

Personalised recommendations