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Properties of an RNA Retrovirus Continuously Produced at Low Levels by a Human Histiocytic Lymphoma Cell Line

  • Henry S. Kaplan
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 57)

Abstract

Type-C RNA viruses (retroviruses) are capable of inducing leukemias, lymphomas, and sarcomas in several mammalian species, including mice, cats, guinea pigs, cattle, and subhuman primates (Kaplan 1974), suggesting that they may also be involved in the etiology of these types of neoplasms in man. Retroviruses have been detected in culture fluids after short-term culture of hematopoietic cells of patients with leukemias (Gallagher and Gallo, 1975; Nooter et al.,1975; Teich et al., 1975) and of diploid human embryonic cell strains (Panem et al., 1975).

Keywords

Lymphoma Cell Line Reverse Transcriptase Activity Peripheral Blood Mononuclear Histiocytic Lymphoma Supernatant Culture Fluid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Henry S. Kaplan
    • 1
    • 2
  1. 1.Cancer Biology Research LaboratoryStanford University School of MedicineStanfordUSA
  2. 2.Department of RadiologyStanford University School of MedicineStanfordUSA

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