Androgen Receptor Assay in Human Prostate Cancer

  • Peter Ekman
  • John Trachtenberg
  • Patrick C. Walsh
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 57)


Because intracellular hormone receptors appear to be necessary for the hormonal dependence of target organs, theoretically steroid receptor measurements should be of value in predicting the response to endocrine therapy for tumors in these target tissues. With this generally accepted concept in mind, much effort has been spent to develop assay methods for steroid receptors in different human cancers. Breast cancer has been extensively studied for more than 10 years and a clear relationship has been demonstrated between the presence of cytosol estrogen receptors and response to endocrine manipulations.1 The clinical correlation can be improved by also taking into account the presence of progestin receptors and measurement of the nuclear compartment.2


Prostatic Cancer Androgen Receptor Human Prostate Steroid Receptor Triamcinolone Acetonide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • Peter Ekman
    • 1
  • John Trachtenberg
    • 1
  • Patrick C. Walsh
    • 1
  1. 1.Brady Urological InstituteThe Johns Hopkins HospitalBaltimoreUSA

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