Derepression and Modulation of Plasminogen Activator in Human Cell Hybrids and Their Segregants
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 57)
Cell fusion has proven to be an useful tool for studying the genetic control of neoplastic transformation and its modulation in vitro (for review see,1–4).
KeywordsPlasminogen Activator Somatic Cell Hybrid Hybrid Line Hybrid Clone Cloning Efficiency
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- 5.L. Ossowski, J. C. Unkeless, A. Tobia, J. P. Quigley, D. B. Rifkin, and E. Reich, An enzymatic function associated with transformation of fibroblast by oncogenic viruses. II. Mam-malian fibroblasts cultures transformed by DNA and RNA tumor viruses, J. exp. Med. 137: 112 (1973).CrossRefGoogle Scholar
- 8.W. E. Laug, P. A. Jones, and W. Benedict, Relationship between fibrinolysis of cultured cells and malignancy, J. nat. Cancer Inst. 54: 173 (1975).Google Scholar
- 9.J. C. Barrett, S. Sheela, 0. Kazunori, and T. Kakunaga, Reexamination of the role of plasminogen activator production for growth in semisolid agar of neoplastic hamster cells, Cancer Res. 40: 1438 (1980).Google Scholar
- 14.L. Larizza, M. L. Tenchini, A. Mottura, E. Rampoldi, M. Colombi, and S. Barlati, Expression of fibronectin and plasminogen activator in human cell hybrids, in “Protides of the Biolo-gical Fluids”, Pergamon Press, in press.Google Scholar
- 17.D. S. Straus, J. Jonasson, and H. Harris, Growth in vitro of tumor cell x fibroblast hybrids in which malignancy is suppressed, J. Cell Sci. 25: 73 (1977).Google Scholar
© Springer Science+Business Media New York 1983